Table 1.
Cases describing relapse of COVID-19 symptoms during out of hospital Paxlovid treatment.
| Case number | Age (years) | Sex | Comorbidities | Medications | Symptom onset | LFT +ve | Paxlovid duration | Symptoms improved | LFT -ve | Symptoms reoccurred | LFT +ve | Hospitalised |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 55 | Male | Rheumatoid arthritis, vasculitis | Rituximab Prednisolone |
Day 1 | Day 1 | Day 2 to Day 6 | Day 5 to Day 7 | Day 6 | Day 8 | Day 8 | No |
| 2 | 44 | Female | Crohn's disease | Ustekinumab | Day 1 | Day 1 Day 2 Day 3 |
Day 4 to Day 9 | Day 5 to Day 11 | Day 5 to Day 11 | Day 14 | Day 14 (x3) Day 15 |
No |
| 3 | 59 | Female | Vasculitis | Rituximab Mycofenolate Prednisolone Hydroxychloroquine |
Day 1 | Day 1 | Day 2 to Day 7 | Day 3 to Day 5 | Day 6 | Day 19 | Day 19 | Assessed but not admitted |