Table 2.
Patient characteristics and factors associated with incomplete sputum smear microscopy monitoring (n = 492)
| Incomplete smears (n= 272) n (%) | Complete smears (n = 220) n (%) | Unadjusted χ2 P value* | OR (95%CI) | aOR (95%CI) | |
|---|---|---|---|---|---|
| Sociodemographic factors | |||||
| Age, years | |||||
| 0–24 | 46 (16.9) | 43 (19.6) | — | — | |
| 25–34 | 83 (30.5) | 69 (31.4) | 0.66 | 1.1 (0.7–1.9) | |
| 35–44 | 68 (25.0) | 49 (22.3) | 0.36 | 1.3 (0.8–2.3) | |
| 45–54 | 39 (14.3) | 30 (13.6) | 0.55 | 1.2 (0.7–2.3) | |
| ≥55 | 36 (13.2) | 29 (13.2) | 0.65 | 1.2 (0.6–2.2) | |
| Sex | |||||
| Female | 75 (27.6) | 81 (36.8) | — | — | — |
| Male | 197 (72.4) | 139 (63.2) | 0.03 | 1.5 (1.1–2.2) | 1.5 (1.0–2.2) |
| Facility type | |||||
| Hospital | 90 (33.1) | 70 (31.8) | — | — | |
| Health Centre IV | 65 (23.9) | 51 (23.2) | 0.97 | 1.0 (0.6–1.6) | |
| Health Centre III | 117 (43.0) | 99 (45.0) | 0.69 | 0.9 (0.6–1.4) | |
| District | |||||
| Kiboga | 148 (54.4) | 154 (70.0) | — | — | — |
| Kyankwanzi | 124 (45.6) | 66 (30.0) | ˂0.001 | 2.0 (1.3–2.8) | 2.0 (1.4–2.9) |
| Clinical factors | |||||
| Type of patient | |||||
| New | 258 (94.9) | 201 (91.4) | — | — | |
| Retreatment | 14 (5.1) | 19 (8.6) | 0.13 | 0.6 (0.3–1.2) | |
| DOT | |||||
| On DOT | 188 (69.1) | 172 (78.2) | — | — | — |
| No DOT | 84 (30.9) | 48 (21.8) | 0.03 | 1.6 (1.1–2.4) | 1.7 (1.1–2.7) |
| HIV status | |||||
| Negative | 168 (61.8) | 146 (66.4) | — | — | |
| Positive | 90 (33.1) | 72 (32.7) | 0.67 | 1.1 (0.7–1.6) | |
| Unknown/missing | 14 (5.1) | 2 (0.9) | |||
| Patients on ART* (n = 162) | |||||
| No | 54 (60.1) | 41 (56.9) | — | — | |
| Yes | 33 (36.6) | 30 (41.6) | 0.58 | 0.8 (0.4–1.6) | |
| Unknown/missing | 3 (3.3) | 1 (1.5) | |||
| Treatment outcomes† | |||||
| Successful | 222 (81.6) | 202 (91.8) | — | — | |
| Unsuccessful | 50 (18.4) | 18 (8.2) | ˂0.01 | 2.5 (1.4–4.5) |
ART status based on documentation in the tuberculosis register.
Successful treatment outcome was defined as cured and completed; unsuccessful treatment outcome included died, defaulted and treatment failure. Patients who died or defaulted from treatment during the intensive phase were censored from the analysis; these included only the 492 patients who were on treatment starting at month 2. Treatment outcomes variable was excluded from multivariable analysis due to lack of interpretability when adjusting for outcome as an independent variable.
OR = odds ratio; CI = confidence interval; aOR = adjusted OR; DOT = directly observed treatment; HIV = human immunodeficiency virus; ART = antiretroviral treatment.