. Author manuscript; available in PMC: 2023 Apr 1.

Published in final edited form as: PM R. 2021 Jun 17;14(4):472–485. doi: 10.1002/pmrj.12623

TABLE 2.

Mean metabolite ratios and their standard deviations in the TBI and control groups in whole-brain gray and white matter

Metabolite	ROI	TBI group	Controls	Mean difference 95% CI	t	df	P value
Metabolite	ROI	Mean (SD)	Mean (SD)	Mean difference 95% CI	t	df	P value

CHO/CR	Gray matter	0.197 (0.030)	0.192 (0.023)	0.004 (−0.020, 0.029)	0.380	19	.708
	White matter	0.261 (0.031)	0.252 (0.025)	0.009 (−0.017, 0.035)	0.724	19	.478
MI/CR	Gray matter	0.516 (0.082)	0.456 (0.056)	0.061 (−0.004, 0.126)	1.950	19	.066
	White matter	0.648 (0.123)	0.587 (0.062)	0.061 (−0.030, 0.151)	1.404	19	.177
NAA/CR	Gray matter	0.596 (0.141)	0.587 (0.106)	0.009 (−0.105, 0.124)	0.170	19	.867
	White matter	1.220 (0.110)	1.291 (0.095)	−0.072 (−0.166, 0.023)	−1.582	19	.130

Note: t-values and P values are from independent-samples t-tests comparing the metabolite ratio means.

Abbreviations: CHO/CR, choline/creatine; CI, confidence interval; MI/CR, myo-inositol/creatine; NAA/CR, N-acetylaspartate/creatine; ROI, region of interest; TBI, traumatic brain injury.