Table 1.
Baseline patient characteristics in Covid-19 patients compared to controls
Characteristic | Covid-19 decedent (N = 10) | Non Covid-19 decedent (N = 20) | P value |
---|---|---|---|
Age | 63.8 (43-82) | 58.6 (34-83) | 0.28 |
GenderMaleFemale | 7 (70) 3 (30) | 12 (60)8 (40) | 0.7 |
Duration of symptoms (days) | 22.2 (5–40) | 16.9 (7–58), n = 12 | 0.34 |
Duration of hospitalization (days) | 16.4 (5–35) | 9.1(1–28), n = 18 | 0.06 |
Obesity (BMI >30 kg/m^2) | 7 (70) | 9 (45) | 0.26 |
Hypertension | 7 (70) | 12 (60) | 0.44 |
Diabetes mellitus | 6 (60) | 4 (20) | 0.11 |
Hyperlipidemia | 5 (50) | 9 (45) | 1.00 |
Underlying CHF | 4 (40) | 3 (15) | 0.18 |
Cardiac arrest (during the last admission) | 4 (40) | 5 (25) | 0.43 |
Ischemic encephalopathy | 0 (0) | 1 (5) | 1 |
peripheral circulatory support (ECMO) | 0 (0) | 0 (0) | 1 |
Intubation | 9 (90) | 13 (65) | 0.2 |
Mean duration of intubation | 11.1 (1–26), n = 9 | 6.3 (1–26), n = 13 | 0.051 |
Mechanical ventilation | 9 (90) | 13 (65) | 0.2 |
SpO2 (last measured) | 80.4 (55–100), n = 10 | 73.2 (40–100) n = 18 | 0.37 |
Renal replacement therapy (dialysis) | 5 (50) | 6 (30) | 0.42 |
Use of pressors | 7 (70) | 13 (65) | 1 |
Cases with elevated troponin | 3 (30), n = 9 | 6 (30), n = 15 | 0.66 |
Peak troponin (ng/L)a | 1.7 (0.02–15.2), n = 9 | 0.13 (0–0.4), n = 15 | 0.46 |
Cases with decreased ejection fraction | 2 (20), n = 6 | 1 (5), n = 16 | 0.16 |
Cases with elevated D-dimer | 9 (90), n = 9 | 6 (30), n = 8 | 0.2 |
Baseline creatinine (mg/dL) | 2.1 (0.78–4.99) | 2.4 (0.3–8.2), n = 18 | 0.72 |
Immediate cause of death due to bronchopneumonia/ diffuse alveolar damage | 7 (70) | 14 (70) | 1.0 |
Other immediate causes of death | Sepsis: 2 (20) | Sepsis: 6 (30) | |
PE: 1 (10) |
Data refer to number (percentage) of patients or mean (range).
CHF, congestive heart failure; CAD, coronary artery disease; SpO2, oxygen saturation.
For each characteristic, when information regarding the characteristic was not available for all of the patients in the group, the number of patients is noted as n = x.
Highest troponin value available in the last admission.