Table 2.
Baseline patient characteristics of Covid-19 patients with single myocyte necrosis compared to Covid-19 patients without single myocyte necrosis
Characteristic | Covid-19 decedents with myocyte necrosis (N = 5) | Covid-19 decedents without myocyte necrosis (N = 5) | P value |
---|---|---|---|
Age | 60 (53–70) | 68 (43–82) | 0.33 |
Gender MaleFemale | 2 (40) 3 (60) | 5 (100)0 (0) | 0.16 |
Duration of symptoms | 26.4 (13–40) | 18 (5–28) | 0.22 |
Duration of hospitalization | 22 (8–35) | 10.8 (5–23) | 0.08 |
Obesity (BMI >30 kg/m^2) | 4 (80) | 3 (60) | 1.00 |
Hypertension | 4 (80) | 3 (60) | 1.00 |
Diabetes mellitus | 3 (60) | 3 (60) | 1.00 |
Hyperlipidemia | 2 (40) | 3 (60) | 1.00 |
Underlying CHF | 2 (40) | 2 (40) | 1.00 |
Cardiac arrest (during the last admission) | 0 (0) | 4 (80) | 0.047 |
Ischemic encephalopathy | 0 (0) | 0 (0) | 1 |
peripheral circulatory support (ECMO) | 0 (0) | 0 (0) | 1 |
Intubation | 5 (100) | 4 (80) | 1 |
Mean duration of intubation | 15.6 (6-26), n=5 | 5.5 (1-9), n=4 | 0.049 |
Mechanical ventilation | 5 (100) | 4 (80) | 1 |
SpO2 (last measured) | 85.6 (59–100), n = 5 | 75.2 (55–100), n = 5 | 0.39 |
Renal replacement therapy (dialysis) | 4 (80) | 1 (20) | 0.2 |
Use of pressors | 5 (100) | 2 (40) | 0.16 |
Cases with elevated troponin | 2 (40) | 1 (20), n = 4 | 1.00 |
Peak troponin (ng/L)a | 3 (0.02–15.2) | 0.077 (0.03–0.18), n = 4 | 0.37 |
Cases with decreased ejection fraction | 1 (20), n = 4 | 1 (20), n = 3 | 1.00 |
Cases with elevated D-dimer | 5 (100) | 4 (100), n = 4 | 1.00 |
Baseline creatinine (mg/dL) | 2.3 (0.9–4.99) | 1.9 (0.7–3.4) | 0.63 |
Immediate cause of death due to bronchopneumonia/ diffuse alveolar damage | 3 (60) | 4 (800) | 1.00 |
Other immediate causes of death | Sepsis: 2 (40) | PE: 1 (20) |
Data refer to number of patients (percentage) or mean (range) unless specified.
CHF, congestive heart failure. CAD, coronary artery disease. SpO2, oxygen saturation.
For each characteristic, when information regarding the characteristic was not available for all of the patients in the group, the number of patients is noted as n = x.
Highest troponin value available in the last admission.