Table 4.
Microscopic and gross pathological findings in Covid-19 patients with single myocyte necrosis compared to Covid-19 patients without single myocyte necrosis.
Characteristic | Covid-19 decedent with myocyte necrosis (N = 5) | Covid-19 decedent without myocyte necrosis (N = 5) | P value |
---|---|---|---|
Heart weight (grams) | 436 (300–640) | 490 (150–650) | 0.63 |
Thickness of left ventricular wall (cm) | 1.62 (1.3–1.9) | 1.5 (1.3–1.7) | 0.34 |
Thickness of right ventricular wall (cm) | 0.52 (0.4–0.6) | 0.58 (0.4–0.7) | 0.36 |
Mean percentage of coronary artery stenosis | 50 (10–80) | 37 (15–50) | 0.47 |
Pleural effusion | 5 (100) | 2 (40) | 0.16 |
Thrombosis | 2 (40) | 2 (40) | 1 |
Epicardial macrophages per mm2 | 99.2 (80–112) | 61.6 (18–81) | 0.02 |
Myocardial macrophages per mm2 | 75.8 (41–130.6) | 49 (10.2–77.7) | 0.22 |
Cases with transmural myocytolysis | 4 (80) | 5(100) | 1 |
Cases with transmural edema | 5 (100) | 4 (80) | 1 |
Cases with microvascular thrombosis | 0 (0) | 0 (0) | 1 |
Data refer to number of patients (percentage) or mean (range) unless specified.
PE, pulmonary embolism.
For each characteristic, when information regarding the characteristic was not available for all of the patients in the group, the number of patients is noted as n = x.