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. 2022 Jun 20;23(8):1279–1282. doi: 10.1016/j.jamda.2022.06.006

Table 2.

Discordance Between Rapid Antigen and Follow-Up PCR Tests for Antigen Tests Done during a Facility Outbreak vs No Outbreak

No Outbreak
Outbreak
Overall Symptomatic Asymptomatic Overall Symptomatic Asymptomatic
Total antigen tests, n 65,442 1121 64,321 105,627 1931 103,696
Antigen tests with a follow-up PCR test, n (%) 3143 (4.8%) 184 (16.4%) 2959 (4.6%) 11,577 (11.0%) 439 (22.7%) 11,138 (10.7%)
Negative antigen tests with positive follow-up PCR test, n 11 0 11 797 58 739
 % of total antigen tests with discordant PCR 0.02% 0% 0.02% 0.8% 3.0% 0.7%
 % of repeated tests with discordant PCR 0.3% 0% 0.4% 6.9% 13.2% 6.6%
Positive antigen tests with negative follow-up PCR test, n 16 0 16 296 13 283
 % of total antigen tests with discordant PCR 0.02% 0% 0.02% 0.3% 0.7% 0.3%
 % of repeated tests with discordant PCR 0.5% 0% 0.5% 2.6% 3.0% 2.5%

All vendors, repeat PCR within 1 day. Symptomatic vs asymptomatic determined based on whether the resident had new onset symptoms in the 5 days prior to testing. Outbreak is defined as 1+ new resident SARS-CoV-2 case(s) in the facility in the 14 days prior to the test. Data as of January 10, 2021. Note, total antigen tests here = 171,069 vs. 171,280 in Table 1 due to some missing daily census data needed to determine outbreak status at time of testing.