Table 1.
Patient-Level and Cluster-Level Characteristics.*
| Patient-level characteristics | ||
| Female sex — no. (%) | 3289 (59.3) | 3112 (61.0) |
| Age at evaluation | ||
| Median age (IQR) — yr | 40 (30–52) | 38 (27–50) |
| Distribution — no. (%) | ||
| 18–29 yr | 1309 (23.6) | 1539 (30.2) |
| 30–39 yr | 1267 (22.8) | 1149 (22.5) |
| 40–49 yr | 1163 (21.0) | 1060 (20.8) |
| ≥50 yr | 1807 (32.6) | 1350 (26.5) |
| HIV infection status — no./total no. (%)† | ||
| Positive | 2285/5273 (43.3) | 1905/4290 (44.4) |
| Negative | 2988/5273 (56.7) | 2385/4290 (55.6) |
| Cluster-level characteristics | ||
| No. of health centers | 10 | 10 |
| Level of health center — no. (%)‡ | ||
| III | 6 (60) | 8 (80) |
| IV | 4 (40) | 2 (20) |
| Location — no. (%) | ||
| Rural | 7 (70) | 8 (80) |
| Urban | 3 (30) | 2 (20) |
| Median distance to molecular testing hub (IQR) — km | 20.5 (6–32) | 15 (13–23) |
| Median prevalence of HIV infection in prerandomization period (IQR) — % of patients | 34.3 (26.0–43.2) | 35.0 (29.9–47.7) |
| Health center region — no. (%) | ||
| Central Uganda | 7 (70) | 6 (60) |
| Eastern Uganda | 3 (30) | 4 (40) |
*
IQR denotes interquartile range, and HIV human immunodeficiency virus.
†
The analysis excluded 1081 patients with unknown status regarding HIV infection.
‡
Level III and IV health centers are at the lowest levels of the health system where tuberculosis diagnostic and treatment services are provided. Level III health centers offer outpatient medical services only and are managed by a senior clinical officer with a diploma in clinical medicine. Level IV health centers offer those services in addition to emergency surgical services and are managed by a medical officer with a bachelor’s degree in medicine.