Table 2.
Clinical trajectory over the 12-month follow-up period.
| Onset | 12 months | p-value | |
|---|---|---|---|
| n (%) | n (%) | ||
| Overall symptoms, number | <0.001 | ||
| 0 | 66 (13.8) | 253 (52.8) | |
| 1 | 66 (13.8) | 92 (19.2) | |
| 2 | 97 (20.2) | 59 (12.3) | |
| 3 | 74 (15.4) | 34 (7.1) | |
| 4 | 76 (15.9) | 12 (2.5) | |
| ≥5 | 100 (20.9) | 29 (6.1) | |
| Mental health domain-related symptoms | 205 (42.8) | 141 (29.4) | <0.001 |
| Symptoms of psychiatric disorders (depression, anxiety, insomnia) | 4 (0.8) | 49 (10.2) | <0.001 |
| Lack of concentration and focus | 14 (2.9) | 96 (20.0) | <0.001 |
| Fatigue | 201 (42.0) | 50 (10.4) | <0.001 |
| Feeling of needing psychological support (n/N) | 57/398 (14.3) | ||
| Feeling of being recovered (n/N) | 351/466 (75.3) | ||
| Neurological domain-related symptoms | 192 (40.1) | 36 (7.5) | <0.001 |
| Headache | 168 (35.1) | 24 (5.0) | <0.001 |
| Neurological symptoms | 31 (6.5) | 13 (2.7) | 0.004 |
| Anosmia/dysgeusia | 268 (55.9) | 53 (11.1) | <0.001 |
| Rheumatological symptoms | 66 (13.8) | 61 (12.7) | 0.578 |
| Respiratory domain-related symptoms | 296 (61.8) | 67 (14.0) | <0.001 |
| Dyspnoea | 156 (32.6) | 44 (9.2) | <0.001 |
| URTI symptoms | 51 (10.6) | 6 (1.2) | <0.001 |
| Cough | 213 (44.5) | 13 (2.7) | <0.001 |
| Chest pain | 19 (4.0) | 13 (2.7) | 0.273 |
| Cutaneous symptoms | 7 (1.5) | 6 (1.2) | 0.781 |
| Gastrointestinal symptoms | 173 (36.1) | 17 (3.5) | <0.001 |
URTI, upper respiratory tract infection.