Table 2.
Determination of the studied drugs in the synthetic mixtures by the proposed spectrophotometric methods.
| Ternary Mixture | |||||||
|---|---|---|---|---|---|---|---|
| Recovery%*± SD | |||||||
| VAL:AML: HCT | VAL(D0) |
AML(D0) | HCT(D0) |
||||
| Ratio (µg/mL) | SS of D0 HCT via AE | SS of D0 HCT via PE |
SS of D0 HCT via RE |
CM | AE | PE | RE |
| (32.0:6.0:2.5) ** | 98.86 | 100.23 | 99.80 | 100.24 | 100.51 | 100.36 | 99.26 |
| (16.0:6.0:2.5) ** | 100.36 | 99.45 | 99.28 | 99.38 | 99.46 | 99.52 | 99.84 |
| (10.0:10.0:10.0) | 99.57 | 100.68 | 100.25 | 100.35 | 100.82 | 99.87 | 100.41 |
| (42.0:7.0:14.0) | — | — | 100.44 | 99.44 | — | — | 100.25 |
| (20.0:10.0:20.0) | 100.44 | 100.55 | 98.56 | 99.58 | 100.23 | 100.24 | 99.56 |
| Mean ± SD | 99.81 ± 0.74 | 100.23 ± 0.55 | 99.67 ± 0.76 | 99.80 ± 0.46 | 100.26 ± 0.58 | 100.00 ± 0.38 | 99.86 ± 0.48 |
* Average of 3 replicates.
** Ratio as dosage forms enriched with 5.0 µg/mL AML.