Figure 2.

Metabolomics and Proteomics changes associated with COVID-19

(A) Volcano plot showing differentially expressed metabolites between COVID-19 patients and controls at an adjusted p value <0.05. In red, upregulated metabolites in COVID-19 patients. In blue, upregulated metabolites in the control group.

(B) Top three differentially expressed metabolites in COVID-19 patients vs. controls based on adjusted p values. Y axis shows log2 fold changes in relation to the mean of the control group.

(C) Number of significantly regulated molecules in KEGG pathways, top 15 shown.

(D) Volcano plot showing the differentially expressed proteins between COVID-19 patients and controls at an adjusted p value <0.05.

(E) Top three differentially expressed proteins in COVID-19 patients vs. controls based on adjusted p values. Y axis shows log2 fold changes in relation to the mean of the control group.

(F) Number of significantly regulated molecules in KEGG pathways, top 15 shown.