Table 2.
Generalized Linear Mixed Models analysis of clinical parameters, ventilator type and time change during the clinical testing procedure.
| N | ICU ventilator | Luca ventilator | Ventilator type | Cohen's f2 | Cohen's D | |
|---|---|---|---|---|---|---|
| Heart rate (/min) | 210 | 87.39 ± 16.81 | 87.97 ± 16.70 | p = 0.225 | 0.004 | 0.035 |
| BP systolic (mmHg) | 210 | 120.48 ± 19.35 | 123.73 ± 21.95 | p = 0.009 | 0.038 | 0.157 |
| BP diastolic (mmHg) | 210 | 58.88 ± 11.36 | 60.4 ± 12.17 | p = 0.010 | 0.007 | 0.129 |
| SpO2 (%) | 210 | 96.30 ± 1.57 | 96.46 ± 1.91 | p = 0.272 | 0.030 | 0.093 |
| Measured respiratory rate (/min) | 210 | 17.02 ± 4.83 | 17.08 ± 4.10 | p = 0.532 | 0.020 | 0.013 |
| pH | 58 | 7.43 ± 0.07 | 7.43 ± 0.06 | p = 0.244 | 0.031 | 0.079 |
| pCO2 (mmHg) | 58 | 34.12 ± 6.07 | 34.57 ± 5.58 | p = 0.278 | 0.028 | 0.078 |
| pO2 (mmHg) | 58 | 93.20 ± 17.92 | 97.30 ± 20.54 | p = 0.106 | 0.017 | 0.213 |
| HCO3 (mmol/L) | 58 | 22.59 ± 3.73 | 22.64 ± 3.81 | p = 0.824 | 0.054 | 0.015 |
| Lactate (mmol/L) | 58 | 1.43 ± 0.84 | 1.39 ± 0.82 | p = 0.304 | 0.014 | 0.050 |
| Measured PEEP (cmH2O) | 210 | 9.46 ± 3.09 | 9.4 ± 3.09 | p = 0.005 | 0.014 | 0.021 |
| Measured inspiratory pressure (cmH2O) | 210 | 23.38 ± 4.44 | 23.56 ± 4.31 | p = 0.026 | 0.018 | 0.069 |
| Inspiratory peak flow (L/s) | 164 | 61.71 ± 9.42 | 67.65 ± 10.02 | p = 0.000 | 0.036 | 0.610 |
| Expiratory peak flow (L/s) | 124 | 24.85 ± 47.13 | 28.12 ± 47.32 | p = 0.086 | 0.073 | 0.069 |
| Tidal volume (mL) | 208 | 581.80 ± 107.19 | 567.63 ± 81.39 | p = 0.184 | 0.046 | 0.149 |
| Minute ventilation (L/min) | 208 | 11.30 ± 12.38 | 11.04 ± 11.14 | p = 0.767 | 0.009 | 0.021 |
| FiO2 (%) | 201 | 0.31 ± 0.05 | 0.31 ± 0.05 | p = 0.103 | 0.058 | 0.012 |
| Set PEEP (cmH2O) | 208 | 9.60 ± 3.11 | 9.57 ± 3.15 | p = 0.416 | 0.049 | 0.010 |
| Set inspiratory pressure (cmH2O) | 210 | 22.97 ± 4.21 | 23.26 ± 4.12 | p = 0.000 | 0.008 | 0.042 |
| Set respiratory rate (/min) | 210 | 13.00 ± 2.46 | 13.00 ± 2.46 | p = 1.00 | 0.086 | 0.000 |
| Ti (s) | 210 | 1.11 ± 0.18 | 1.11 ± 0.18 | p = 0.061 | 0.013 | 0.016 |
| Alarm (/h) | 105 | 0.03 ± 0.17 | 0.22 ± 0.69 | p = 0.07 |
BP: blood pressure, HCO3: bicarbonate, FiO2: fraction of inspired oxygen, pCO2: partial pressure of carbon-dioxide, PEEP: positive end expiratory pressure, pO2: partial pressure of oxygen, SpO2: oxygen saturation, Ti: inspiratory time.
Measurement numbers (N) are a result of available data point values. Cohen's D (the difference between two groups’ means in standard deviation) is considered small if the value is less than 0.2, medium if less than 0.5 and large if more than 0.8. A small Cohen's D values suggests that the difference is negligible, even if it is statistically significant. Cohen's f2 (the square of the difference between two groups’ means in standard deviation) is considered small if the value is less than 0.02, medium if less than 0.15 and large if more than 0.35. A small Cohen's f2 value suggests that the difference is negligible, even if it is statistically significant.