Table 3.
Laboratory data at admission and follow up.b
| Laboratory data – no. (%) | Admission (n = 82)a | 48 h (n = 79)a | 7 days (n = 51)a |
|---|---|---|---|
| Red cell count | |||
| Haemoglobin, mean – g/dl | 13.3 ± 1.6 | 12.7 ± 1.6 | 12.5 ± 1.5 |
| ≥10 g/dl – no. (%) | 78 (96.3%) | 41 (93.2%) | 43 (95.6%) |
| White cell count | |||
| Mean (SD) – per mm3 | 9.2 ± 10.4 | 6.7 ± 3.8 | 7.1 ± 3.5 |
| Distribution – no. (%) | |||
| ≥10,000/mm3 | 17 (21.3%) | 5 (11.4%) | 9 (20%) |
| ≤4000/mm3 | 7 (8.8%) | 10 (22.7%) | 9 (20%) |
| Lymphocyte count | |||
| Median (IQR) – per mm3 | 868.9 (593.7–1205.5) | 710.5 (491.5–1154.9) | 1112.0 (575.1–1519.6) |
| Distribution – no. (%) | |||
| ≥1000/mm3 – no. (%) | 34 (42.5%) | 15 (34.1%) | 23 (51.1%) |
| Platelet count, mean – per mm3 | 199 ± 87.2 | 235.7 ± 139.4 | 282.3 ± 141.6 |
| Prothrombin time, mean – % | 77.9 ± 23.8 | ||
| Activated partial thrombopastin time, mean – seconds | 24.6 ± 9.8 | ||
| Fibrinogen, mean – g/dl | 5.6 ± 1.0 | ||
| D dimer, median (IQR) – ng/mL | 295 (201–437) | 565 (303–772) | 738 (273.5–2963) |
| Glucose, mean – mg/dl | 120.2 ± 36.7 | ||
| Urea, median (IQR) – mg/dl | 43 (38–72) | ||
| Serum creatinine, mean – mg/dl | 1.7 ± 6.1 | 2.1 ± 7.1 | 0.9 ± 0.6 |
| Glomerular filtrate, mean – CKD-EPI | 73.5 ± 23.8 | 73.1 ± 26.5 | 77.25 ± 19.9 |
| Sodium, mean – mmol/L | 136.0 ± 3.7 | ||
| Potasium, mean – mmol/L | 3.9 ± 0.7 | ||
| Calcium, mean – mg/dl | 8.9 ± 0.5 | ||
| Total bilirubin, mean – mg/dl | 0.7 ± 0.5 | ||
| Aspartate aminotransferase, mean – U/litre | 53.1 ± 34.3 | 53.7 ± 35.4 | 71.4 ± 46.2 |
| Aspartate aminotransferase > 40 U/litre | 42 (53.9%) | 25 (61%) | 30 (66.7%) |
| Alanine aminotransferase, mean – U/litre | 41.68 (34.4) | 43.4 (31.7) | 77.3 (71) |
| Alanine aminotransferase > 40 U/litre | 28 (35.4%) | 16 (39.0%) | 30 (66.7%) |
| Alkaline phosphatase, mean – U/litre | 69.80 ± 21.7 | ||
| Gamma-glutamyl transferase, mean – U/litre | 93 ± 58.0 | ||
| LDH, mean – UI/L | 446.61 ± 79.5 | ||
| CRP, mean – mg/dl | 17.98 ± 11.7 | 17.5 ± 10.0 | 6.3 ± 9.2 |
| Ferritin, mean – ng/mL | 885.69 ± 500.5 | 1505.4 ± 1194.6 | 1241.6 ± 789.2 |
| Proteins, mean – g/dl | 7.38 ± 0.7 | ||
| Albumin, mean – g/dl | 3.30 ± 0.3 | ||
| IL-6, median (IQR) – pg/mL | 74.8 (49.4–120.0) | 184.1 (75.3–592.6) | 501.2 (103.7–2361.0) |
| Infection analysis | |||
| Positive blood cultures | 1 (1.3%) | 0 (0%) | 1 (10%) |
| Positive sputum cultures | 3 (4.3%) | 0 (0%) | 2 (22.2%) |
| Positive pneumococcal urinary antigen | 2 (2.5%) | 0 (0%) | 0 (0%) |
a
Total number of patients varies among variables and follow up as mortality increases.
b
Plus-minus values are means (±SD). Rounding has been applied to percentages. Total may no be 100 because of rounding.