Emergence of bamlanivimab resistance mutations correlates with recrudescent shedding of culturable virus
(A) Viral load and culture positivity at baseline and day 1 post-treatment for four study participants with recrudescent shedding of culturable virus. Cx, culture.
(B–E) Viral load and TCID50 for four study participants whose infecting virus developed E484 mutations of the spike protein following bamlanivimab monotherapy.