Table 1.
Susceptibility of Candida Isolates to 25 μg Fluconazole
| Candida Isolate | Strain | Zone of Inhibition (mm)* at 24 h | MIC (μg/mL)# at 24 h | Zone of Inhibition (mm)* at 48 h | MIC (μg/mL)# at 48 h | Remarks |
|---|---|---|---|---|---|---|
| SC5314 | C. albicans | 33 ± 1 | 1.14 ± 0.4 | 35 ± 1 | 1.25 ± 0 | Susceptible |
| Can Iso–001 | C. albicans | 0 ± 0 | 70.2 ± 0.1 | 0 ± 0 | 72.1 ± 0.2 | Resistant |
| Can Iso–002 | C. krusei | 28 ± 2 | 23.2 ± 0.8 | 30 ± 1 | 25.32 ± 0.5 | Susceptible |
| Can Iso–003A | C. glabrata | 30 ± 1 | 0.42 ± 0.2 | 36 ± 1 | 0.84 ± 0.4 | Susceptible |
| Can Iso–003B | C. krusei | 24 ± 1 | 23.19 ± 0 | 24 ± 2 | 26.31 ± 0.8 | Susceptible |
| Can Iso–004 | Other species | 33 ± 3 | 1.18 ± 0.7 | 33 ± 1 | 1.3 ± 0.8 | Susceptible |
| Can Iso–005 | Other species | 23 ± 2 | 1.4 ± 0.9 | 26 ± 2 | 1.54 ± 0.9 | Susceptible |
| Can Iso–006 | Other species | 29 ± 2 | 1.4 ± 0.7 | 30 ± 2 | 1.54 ± 0 | Susceptible |
| Can Iso–007 | C. tropicalis | 38 ± 2 | 0.64 ± 0.9 | 39 ± 1 | 1.2 ± 0.5 | Susceptible |
| Can Iso–008A | Other species | 21 ± 1 | 1.3 ± 0 | 22 ± 2 | 1.43 ± 0.4 | Susceptible |
| Can Iso–008B | C. albicans | 14 ± 1 | 1.15 ± 0.9 | 15 ± 1 | 1.27 ± 0.9 | Resistant |
| Can Iso–009 | C. albicans | 29 ± 1 | 1.2 ± 0.5 | 29 ± 1 | 1.34 ± 0.6 | Susceptible |
| Can Iso–010 | C. albicans | 30 ± 1 | 1.3 ± 0.5 | 33 ± 1 | 1.43 ± 0.9 | Susceptible |
| Can Iso–011 | C. albicans | 26 ± 2 | 1.11 ± 0.2 | 26 ± 2 | 1.22 ± 0.9 | Susceptible |
| Can Iso–012 | Vther species | 25 ± 2 | 1.3 ± 0 | 26 ± 1 | 1.43 ± 0.5 | Susceptible |
| Can Iso–013 | C. albicans | 20 ± 2 | 1.3 ± 0 | 22 ± 1 | 1.43 ± 0.3 | Susceptible |
| Can Iso–014A | C. krusei | 22 ± 2 | 24.4 ± 0.8 | 24 ± 1 | 34.59 ± 0.6 | Susceptible |
| Can Iso–014B | C. glabrata | 30 ± 1 | 0.4 ± 0.9 | 30 ± 1 | 0.88 ± 0 | Susceptible |
| Can Iso–014c | Other species | 20 ± 3 | 1.13 ± 0.1 | 24 ± 1 | 1.24 ± 0.6 | Susceptible |
| Can Iso–015 | C. albicans | 21 ± 2 | 1.21 ± 0.8 | 22 ± 1 | 1.33 ± 0.4 | Susceptible |
| Can Iso–016 | Other species | 18 ± 1 | 16.21 ± 0.3 | 20 ± 1 | 21.35 ± 0.3 | SSD |
| Can Iso–017 | C. albicans | 17 ± 2 | 25.3 ± 0.1 | 20 ± 2 | 30.43 ± 0.2 | SSD |
| Can Iso–018 | Other species | 24 ± 1 | 1.4 ± 0.1 | 26 ± 1 | 1.54 ± 0.9 | Susceptible |
| Can Iso–019A | C. krusei | 19± 2 | 1.31 ± 0.1 | 25 ± 1 | 1.44 ± 0 | Susceptible |
| Can Iso–019B | C. tropicalis | 25 ± 2 | 0.63 ± 0.6 | 28 ± 1 | 1.1 ± 0 | Susceptible |
| Can Iso–020A | Other species | 21 ± 1 | 0.5 ± 0.7 | 25 ± 2 | 0.67 ± 0 | Susceptible |
| Can Iso–020B | C. albicans | 19 ± 3 | 2.1 ± 0.1 | 22 ± 2 | 2.31 ± 0.3 | Susceptible |
| Can Iso–001C | C. glabrata | 29 ± 1 | 0.4 ± 0.5 | 31 ± 1 | 0.89 ± 0 | Susceptible |
| Can Iso–021 | Other species | 26 ± 2 | 1.6 ± 0.5 | 32 ± 1 | 1.76 ± 0.7 | Susceptible |
| Can Iso–022A | Other species | 19 ± 1 | 1.4 ± 0.8 | 21 ± 1 | 1.54 ± 0.7 | Susceptible |
| Can Iso–022B | C. albicans | 30 ± 1 | 1.18 ± 0.9 | 38 ± 1 | 1.3 ± 0 | Susceptible |
| Can Iso–023 | C. albicans | 28 ± 1 | 2.7 ± 0.8 | 33 ± 1 | 2.97 ± 0 | Susceptible |
| Can Iso–024A | C. albicans | 29 ± 1 | 1.30± 0.4 | 31 ± 1 | 1.43 ± 0.8 | Susceptible |
| Can Iso–024B | Other species | 20 ± 2 | 1.5 ± 0.3 | 21 ± 1 | 1.65 ± 0.2 | Susceptible |
| Can Iso–025 | Other species | 23 ± 1 | 1.1 ± 0 | 24 ± 2 | 1.24 ± 0.6 | Susceptible |
| Can Iso–026 | C. albicans | 25 ± 1 | 1.23 ± 0.4 | 25 ± 1 | 1.35 ± 0.3 | Susceptible |
| Can Iso–027 | Other species | 33 ± 2 | 1.7 ± 0.2 | 33 ± 1 | 1.87 ± 0.5 | Susceptible |
| Can Iso–028 | C. albicans | 38 ± 2 | 1.22 ± 0.8 | 42 ± 2 | 1.34 ± 0 | Susceptible |
| Can Iso–029/dog | C. albicans | 29 ± 1 | 1.8 ± 0 | 39 ± 1 | 1.96 ± 0.7 | Susceptible |
Notes: *Susceptible S, ≥ 19 mm; susceptible dose-dependent SDD, 15 to 18 mm; Resistant R, ≤ 14 mm. #Susceptible S, <or= 8 μ/mL; susceptible-dose dependent (SDD), 16 to 32 μ/mL; Resistance, >or= 64 μ/mL.