Table 1. Muscle histomorphometry means, standard deviations (in parentheses), and statistical results for short (3 months) temporary denervation groups.
| Muscle force (N) | Muscle weight (g) | Type I | Type IIA | Type IIB | Satellite cell count | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Area (µm 2 ) | Diameter (µm) |
Proportion (%) |
Area (µm 2 ) | Diameter (µm) |
Proportion (%) |
Area (µm 2 ) | Diameter (µm) |
Proportion (%) |
||||
| FST protein and denervation | 0.37 (0.19) |
0.64
a
(0.18) |
1,988.8 (803.1) |
37.4
a
(10.1) |
20.3 (6.0) |
1,371.9
a
(554.4) |
29.2
a
(7.5) |
28.7 (7.1) |
1,958.8 (992.0) |
37.4 (10.1) |
51.0 (8.6) |
157.9
a
(29.0) |
| Sham protein and denervation | 0.45 (0.25) |
0.93
a
(0.17) |
3,222.5 (1,068.9) |
48.8
a
(8.5) |
16.8 (3.7) |
3,237.2
a
(779.1) |
48.5
a
(6.0) |
33.5 (13.5) |
2,726.7 (474.2) |
44.4 (3.5) |
49.7 (10.6) |
114.8
a
(12.1) |
| FST protein and sham denervation |
0.98
a
(0.47) |
2.22 (0.17) |
4,379.5 (709.1) |
55.1 (6.4) |
16.5 (4.6) |
4,417.3 (624.3) |
55.9 (5.6) |
43.4 (6.8) |
6,404.0 (1,220.3) |
66.5 (6.4) |
40.4 (6.1) |
134.8
a
(17.0) |
| Sham protein and sham denervation |
1.75
a
(0.60) |
2.42 (0.20) |
4,434.2 (750.2) |
57.9 (5.2) |
19.4 (7.1) |
4,673.8 (404.0) |
58.3 (3.7) |
32.9 (6.6) |
5,592.9 (1,355.8) |
62.6 (7.2) |
47.7 (6.7) |
153.0
a
(16.7) |
Abbreviations: FST, follistatin; N, newton; µm, micrometers.
a
Denotes significant differences between treatment and matched sham treatment at p <0.05.