Table 2. Muscle histomorphometry means, standard deviations (in parentheses), and statistical results for long (6 months) temporary denervation groups.
| Muscle force (N) | Muscle weight (g) | Type I | Type IIA | Type IIB | Satellite cell count | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Area (µm 2 ) | Diameter (µm) |
Proportion (%) |
Area (µm 2 ) | Diameter (µm) |
Proportion (%) |
Area (µm 2 ) | Diameter (µm) |
Proportion (%) |
||||
| FST protein and denervation | 0.63 (0.45) |
1.00 (0.53) |
2,268.9 (1,410.1) |
39.0
a
(14.2) |
9.2 (2.9) |
1,942.7 (1,200.2) |
35.6 (12.1) |
24.9 (4.7) |
2,106.1 (1,120.7) |
37.7 (12.1) |
65.9 (3.8) |
179.1
a
(40.0) |
| Sham protein and denervation | 0.20 (0.18) |
0.81 (0.33) |
1,312.0 (953.2) |
28.6
a
(12.2) |
12.1 (2.2) |
1,419.9 (590.4) |
29.5 (7.9) |
20.5 (3.5) |
1,702.4 (1,010.4) |
32.2 (11.8) |
67.3 (2.2) |
104.0
a
(12.2) |
| FST protein and sham denervation | 1.03 (0.40) |
2.33 (0.36) |
4,207.3
a
(1,112.0) |
55.6
a
(9.9) |
9.9 (3.3) |
3,178.6 (675.6) |
45.8 (6.0) |
20.9 (3.2) |
4,836.4
a
(1,322.8) |
56.8
a
(8.5) |
69.2 (5.2) |
147.9 (31.8) |
| Sham protein and sham denervation | 1.29 (0.63) |
2.17 (0.49) |
3,130.2
a
(426.9) |
45.8
a
(4.2) |
8.2 (4.3) |
2,419.1 (435.5) |
39.5 (4.0) |
24.1 (3.3) |
2,666.8
a
(326.6) |
42.2
a
(2.9) |
67.7 (2.9) |
137.5 (8.8) |
Abbreviations: FST, follistatin; N, newton; µm, micrometers.
a
Denotes significant differences between treatment and matched sham treatment at p <0.05.