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TCM-induced neuroprotection by modulation of the MAPK/ERK signaling. Artemisinin, ginsenoside Rb1, and Astragaloside IV from TCM activate the ERK1/2 phosphorylation and preserve a balanced MAPK/ERK phosphorylation activity contributing to a decrease amount of Aβ aggregates and tangles of tau protein in the brain of AD patients.
