Figure 6.
HER2-miR1 overexpression effect on cell cycle status of Wnt+ and Wnt− cells. (a, b) Show HER2-miR1 overexpression effect on SW480 (a) and HCT116 (b) cell cycle distribution, 36 h after transfection, measured by PI. Overexpression of HER2-miR1 resulted in significant G1 elevation and S phase reduction in both SW480 and HCT116 cell lines, compared to the related controls. (c) Overexpression of HER2-miR1 did not significantly change the cell cycle population distribution of HEK293t cell line. Error bars indicate SD of duplicated experiments, P < 0.05.