Table 5.
The type and treatment of adverse reactions (n = 60).
| Adverse reactions | Grade I/II | Grade III | Grade IV | Treatment |
|---|---|---|---|---|
| Hemoglobin reduction | 37 | 0 | 0 | NA |
| Leukocyte reduction | 6 | 0 | 0 | NA |
| Neutropenia | 4 | 0 | 1 | Human granulocyte colony-stimulating factor |
| Thrombocytopenia | 27 | 0 | 0 | NA |
| Transient elevation of myocardial enzyme | 22 | 0 | 0 | NA |
| Proteinuria | 1 | 0 | 0 | NA |
| Hypokalemia | 3 | 0 | 0 | NA |
| Pancreatitis | 0 | 2 | 0 | Drainage and antibiotics |
| Bleeding from duodenal ulcer | 0 | 0 | 1 | Interventional embolization |
| Fever | 10 | 0 | 0 | Antibiotics |
| Diarrhea | 1 | 0 | 0 | Pancreatic enzyme suppletion |
| Nausea and vomiting | 9 | 0 | 0 | Antiemetics |
| Infection | 3 | 0 | 0 | Antibiotics and drainage |
| Abdominal pain | 39 | 0 | 0 | Oral analgesics |
| Loss of appetite and | 9 | 0 | 0 | Nasojejunal tube feeding |
| Mild ascites | 27 | 0 | 0 | NA |
| Mild pleural effusion | 8 | 0 | 0 | NA |
| Abdominal distention | 12 | 0 | 0 | NA |
NA: no receiving further treatment.