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Effect of captopril and HOE140 on bone strength. (a) Captopril increased the maximum load of the proximal femur, and HOE140 further improved it, in both male and female rats. (b) Captopril increased the energy of the proximal femur, and HOE140 further improved it in both male and female rats. Data are shown as mean ± SE. ∗P < 0.05, ∗∗P < 0.001. n = 3.
