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. 2022 May 21;14(5):e25192. doi: 10.7759/cureus.25192

Figure 3. Postoperative pathological findings.

Figure 3

a) Postoperative histopathological findings showed a glandular malignant tumor with strong mucus formation and a signet-ring cell-like tumor with an uneven distribution of nuclei (indicated by arrowheads). b) Immunohistostaining findings showed cytokeratin (CK) AE1/AE3 (+), CK7 (+), CK20 (-), gross cystic disease fluid protein (GCDFP)15 (+), thyroid transcription factor (TTF)1 (-), paired-box-containing (PAX) 8 (-), androgen receptor (AR) (-), mammaglobin (-), and MIB-1 (10-20%). c) In both lobes of the thyroid gland, tumor follicles with ground glass nuclei and nuclear grooves infiltrate and proliferate in papillary, tubular, and follicular forms (shown with arrows). d) In the left cervical lymph node, cancer metastasis is found in 23 lymph nodes, all of which are signet-ring cell/histiocytoid carcinoma (arrowheads). In the right cervical lymph node, cancer metastasis is found in 26 lymph nodes, all of which are metastases of papillary thyroid carcinoma (shown with arrows).