Table 4.

Multiparametric bone MRI (mpBMRI) serial parameter testing performance for identification of successful biopsies

mpBMRI performance	Identification of tumour-positive biopsies	Identification of NGS feasibility
True positive	27/33	20/22
True negative	8/10	7/9
False positive	2	2
False negative	6	2
Sensitivity	82% (65–93%)	91% (71–99%)
Specificity	80% (44–97%)	78% (40–97%)
PPV	93% (80–98%)	91% (75–97%)
NPV	57% (37–74%)	78% (47–93%)

95% confidence interval in brackets; NGS next-generation genomic sequencing, PPV positive predictive value, NPV negative predictive value