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. 2022 May 2;30(8):6641–6648. doi: 10.1007/s00520-022-07090-7

Table 2.

Results of scalp cooling in patients evaluable for hair loss

20-min PICT (n = 38) 45-min PICT (n = 36) 90-min PICT(n = 723, Dutch Scalp Cooling Registry) P value
Primary endpoint (self-determined need to wear head covering)
Patients with head covering 7 (18.4%) 9 (25.0%) 112 (15.5%)
Patients without head covering 31 (81.6%) 27 (75%) 611 (84.5%) 0.29
Secondary endpoints (n = 26) (n = 26)

Dean scale for Alopecia (mean, SD)

Score 0–2

Score 3–4

1.31 (1.01)

21 (80.8%)

6 (19.2%)

1.77 (1.07)

21 (80.8%)

5 (19.2%)

n/a

0.12

1.0

NCI CTCAE grade of alopecia (mean, SD)

Score 0–1

Score 2

1.00 (0.63)

21 (80.8%)

5 (19.2%)

1.15 (0.61)

21 (80.8%)

5 (19.2%)

n/a

0.38

1.0

PICT Post-infusion cooling time, NCI CTCAE National Cancer Institute Common Terminology Criteria for Adverse Events