Table 2.
Mean concentrations and coefficients of variation of free amino acids and their metabolites in the study rats from the plasma concentrations measured at baseline, 2 months, 4 months
| Amino acid | Mean concentration (µM) | Coefficient of variation (%) |
|---|---|---|
| Ala | 286 | 1.4 |
| Thr | 365 | 3.7 |
| Gly | 329 | 7.4 |
| Val | 211 | 11.5 |
| Ser | 293 | 7.2 |
| Sarcosine | 1.24 | 23.6 |
| Leu + Ile | 221 | 10.6 |
| GAA | 4.08 | 17.2 |
| Asp + Asn | 81.9 | 10.8 |
| OH-Pro | 13.1 | 24.5 |
| Pro | 127 | 3.9 |
| Met | 82.2 | 9.2 |
| Glu + Gln | 953 | 8.3 |
| 5-OH-Lys(D) | 0.3 | 3.3 |
| 5-OH-Lys(L) | 0.93 | 3.3 |
| Orn + Cit | 74.6 | 4.8 |
| Phe | 80.2 | 6.9 |
| Tyr | 62.4 | 8.1 |
| Lys | 351 | 6.1 |
| Arg | 122 | 7.7 |
| MML | 0.64 | 19.5 |
| CMC | 1.9 | 6.8 |
| hArg | 0.81 | 21.4 |
| Trp | 76.6 | 9.4 |
| CML | 0.11 | 5.1 |
| ADMA | 0.44 | 12.4 |
| MMA | 0.12 | 8.3 |
| Furosine | 0.04 | 6.4 |
Values above 10.0 are indicated in bold
GAA guanidinoacetate, MML monomethyllysine, CMC carboxymethylcysteine, CML carboxymethyllysine, ADMA asymmetric dimethylarginine, MMA monomethylarginine