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. 2022 May 26;54(6):889–896. doi: 10.1007/s00726-022-03169-x

Table 3.

Assessment of the weight dependence of various homoarginine dosing regimens; given percentage indicate the number of subjects laying > 90% of time in target range

Population Old Old Old Young Young Young
Dosing regimen 60 kg ± 0.5 kg 80 kg ± 0.5 kg All 60 kg ± 0.5 kg 80 kg ± 0.5 kg all
12.5 mg q 24 h 67.5% 37.2% 50.4% 71.5% 38.4% 54.3%
15 mg q 24 h 80.9% 47.0% 63.7% 84.2% 47.6% 67.6%
20 mg q 24 h 87.6% 70.7% 79.6% 92.6% 76.2% 84.1%
25 mg q 24 h 60.4% 79.3% 74.1% 73.8% 84.1% 82.2%
125 mg q 168 h 0.33% 20.1% 9.0% 17.4% 24.4% 22.1%