Table 1.
Demographic and medical characteristics of YACCS: participants versus non-participants/norm group
Participants (N = 558) | Non-participants (N = 858)a | Norm group (N = 655)b | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
M | SD | Range | M | SD | Range | p | M | SD | Range | p | |
Age at study (years) | 25.78 | 3.33 | 18.10–30.97 | 25.48 | 3.45 | 18.01–31.00 | 0.10 | 24.75 | 3.79 | 18.01–30.99 | < 0.001 |
Age at first diagnosis (years) | 4.25 | 3.12 | 0.00–14.67 | 4.31 | 2.99 | 0.00–14.62 | 0.73 | ||||
Time since first diagnosis (years) | 20.92 | 3.31 | 15.02–29.17 | 21.18 | 3.42 | 14.81–30.93 | 0.16 | ||||
N | % | N | % | p | N | % | p | ||||
Sex | < 0.001 | 0.977 | |||||||||
Male | 273 | 48.9 | 530 | 61.8 | 321 | 49.0 | |||||
Female | 285 | 51.1 | 328 | 38.2 | 334 | 51.0 | |||||
Age at first diagnosis (years) | 0.86 | ||||||||||
0–5 | 418 | 74.9 | 644 | 75.1 | |||||||
6–11 | 128 | 22.9 | 199 | 23.2 | |||||||
12–15 | 12 | 2.2 | 15 | 1.7 | |||||||
Time since first diagnosis (years) | 0.19 | ||||||||||
10–19 | 258 | 46.2 | 375 | 43.7 | |||||||
20–29 | 300 | 53.8 | 479 | 55.8 | |||||||
30–39 | 0 | 0.0 | 4 | 0.5 | |||||||
Diagnosisc | 0.76 | ||||||||||
Leukemia/lymphoma | 299 | 53.6 | 453 | 52.8 | |||||||
Solid tumor | 198 | 35.5 | 300 | 35.0 | |||||||
CNS cancerd | 61 | 10.9 | 105 | 12.2 | |||||||
Treatmente | 0.10 | ||||||||||
Chemotherapy only (with/without surgery) | 394 | 70.6 | 585 | 68.3 | |||||||
Radiotherapy only (with/without surgery) | 14 | 2.5 | 33 | 3.9 | |||||||
Surgery alone | 48 | 8.6 | 96 | 11.2 | |||||||
Combination therapy (chemo + radiotherapy, with/without surgery) | 98 | 17.6 | 129 | 15.1 | |||||||
No treatment | 4 | 0.7 | 14 | 1.6 | |||||||
Hematopoietic transplant | 0.03 | ||||||||||
Yes | 46 | 8.3 | 46 | 5.4 | |||||||
No | 511 | 91.7 | 811 | 94.6 | |||||||
Relapse | 0.63 | ||||||||||
Yes | 61 | 10.9 | 101 | 11.8 | |||||||
No | 497 | 89.1 | 757 | 88.2 |
Significant differences between participants and non-participants and between participants and norm group are presented in bold
aYACCS who did not participate in the present study or any other part of the DCCS-LATER study part 2
bThe norm group consists of young adults from the general Dutch population
cFirst, primary diagnosis
dCentral nervous system and miscellaneous intracranial and intraspinal neoplasm
eFor primary cancers and recurrences