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. 2022 May 10;30(8):6839–6849. doi: 10.1007/s00520-022-07113-3

Table 3.

Psychosocial developmental milestones YACCS (total group and CNS cancer) versus the norm group; CoLQ item scores

YACCS total group YACCS CNS cancer Norm group Total vs Norm CNS cancer vs norm
% N % N % N OR [99% CI] OR [99% CI]
(a) Frequencies of the (dichotomized) items of autonomy development
Regular chore in your family, e.g., washing dishes, setting the table; primary school

Yes

  No

33.4

66.6

186

371

29.5

70.5

18

43

39.5

60.5

259

396

0.74 [0.54; 1.01] 0.57 [0.27; 1.22]
Paid jobs/chores outside home, e.g., washing cars, mowing lawns; primary school

  Yes

  No

31.7

68.3

177

381

23.0

77.0

14

47

23.8

76.2

156

499

1.39 [0.99; 1.94] 0.81 [0.35; 1.86]
Regular job/chore in your family, secondary school

  Yes

  No

55.3

44.7

308

249

54.1

45.9

33

28

52.2

47.8

342

313

1.14 [0.84; 1.54] 1.03 [0.51; 2.08]
Paid jobs, secondary school

  At the age of 18 or younger

  At the age of 19 or older/never

81.5

18.5

455

103

62.3

37.7

38

23

85.0

15.0

557

98

0.76 [0.51; 1.14] 0.27a** [0.13; 0.57]
For the first time being on holiday without adults

  At the age of 17 or younger

  At the age of 18 or older/never

44.4

55.6

247

309

21.3

78.7

13

48

42.6

57.4

279

376

1.05 [0.78; 1.42] 0.34a* [0.15; 0.78]
Leaving your parents’ place

  Not living with your parents

  Still living with your parents

69.7

30.3

388

169

65.6

34.4

40

21

65.8

34.2

431

224

0.70 [0.47; 1.06] 0.25a** [0.09; 0.65]
(b) Frequencies of the (dichotomized) items of psychosexual development
First girlfriend/boyfriend

  At the age of 17 or younger

  At the age of 18 or older/never

64.5

35.5

359

198

45.9

54.1

28

33

63.4

36.6

415

240

1.00 [0.73; 1.37] 0.44a* [0.22; 0.89]
For the first time falling in love

  At the age of 18 or younger

  At the age of 19 or older/never

88.8

11.2

492

62

78.7

21.3

48

13

86.6

13.4

567

88

1.16 [0.73; 1.83] 0.51 [0.21; 1.23]
For the first time sexual intimacy

  At the age of 18 or younger

  At the age of 19 or older/never

75.3

24.7

417

137

60.0

40.0

36

24

72.4

27.6

474

181

1.10 [.78; 1.55] 0.48a* [0.23; 0.99]
For the first time sexual intercourse

  At the age of 18 or younger

  At the age of 19 or older/never

59.5

40.5

328

223

32.8

67.2

20

41

57.4

42.6

376

279

1.04 [0.77; 1.42] 0.30a** [0.14; 0.63]
(c) Frequencies of the (dichotomized) items of social development
At least one year of membership in a sports club, primary school

  Yes

  No

84.5

15.5

469

86

91.7

8.3

55

5

80.3

19.7

526

129

1.37 [0.92; 2.04] 2.83 [0.82; 9.75]
Number of friends in first–third grade, primary school

  4 or more

  Less than 4

61.0

39.0

340

217

50.8

49.2

31

30

60.0

40.0

393

262

1.04 [0.76; 1.41] 0.67 [0.33; 1.34]
Number of friends in fourth–sixth grade, primary school

  4 or more

  Less than 4

63.4

36.6

352

203

50.8

49.2

31

30

60.3

39.7

395

260

1.14 [0.84; 1.56] 0.68 [0.34; 1.38]
Best friend, primary school

  Yes

  No

78.7

21.3

437

118

70.5

29.5

43

18

71.9

28.1

471

184

1.39 [0.97; 1.97] 0.81 [0.37; 1.75]
Most of the time playing with …, primary school

  Friends

  Brothers and/or sisters, parents, on your own

81.5

18.5

455

103

72.1

27.9

44

17

84.0

16.0

550

105

0.83 [0.56; 1.23] 0.46 [0.21; 1.02]
At least one year of membership in a sports club, secondary school

  Yes

  No

74.5

25.5

415

142

81.7

18.3

49

11

62.4

37.6

409

246

1.80b** [1.29; 2.50] 2.81b* [1.15; 6.85]
Number of friends, secondary school

  4 or more

  Less than 4

64.5

35.5

360

198

42.6

57.4

26

35

62.0

38.0

406

249

1.15 [0.84; 1.57] 0.46a* [0.23; 0.94]
Best friend, secondary school

  Yes

  No

70.6

29.4

393

164

63.9

36.1

39

22

66.1

33.9

433

222

1.22 [0.88; 1.69] 0.79 [0.38; 1.66]
Belonging to a group of friends, secondary school

  Yes

  No

80.1

19.9

444

110

57.4

42.6

35

26

78.6

21.4

515

140

1.14 [0.79; 1.66] 0.37a** [0.18; 0.76]
Leisure time, mainly with …, secondary school

  Friends

  Brothers and/or sisters, parents, on your own

79.9

20.1

446

112

57.4

42.6

35

26

83.5

16.5

547

108

0.74 [0.50; 1.10] 0.23a** [0.11; 0.48]
Going out to a bar or disco, secondary school

  Sometimes/often

  Never

74.4

25.6

415

143

60.7

39.3

37

24

74.0

26.0

485

170

0.93 [0.66; 1.32] 0.47a* [0.23; 0.99]
At least one year of membership in a sports club, after secondary school

  Yes

  No

53.0

47.0

296

262

57.4

42.6

35

26

39.4

60.6

258

397

1.72b** [1.27; 2.34] 2.22b* [1.09; 4.52]

CNS central nervous system and miscellaneous intracranial and intraspinal neoplasm; OR odds ratio/exponent B; CI confidence interval

*p < 0.01; **p < 0.001; significant differences (p < 0.01) between YACCS and the norm group are presented in bold

aThe proportion of YACCS CNS cancer that achieved the milestone was significantly lower than the proportion in the norm group, according to logistic regression analyses corrected for age and sex

bThe proportion of YACCS CNS cancer that achieved the milestone was significantly higher than the proportion in the norm group, according to logistic regression analyses corrected for age and sex