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. 2021 Dec 8;52(7):1689–1699. doi: 10.1007/s40279-021-01608-5

Table 3.

Effect of change in VO2peak on MoCA score and association with MCI

MoCA score MCI
Mean (SD) Unadjusted
B (95% CI)
Adjusteda
B (95% CI)
Number of cases (%) Unadjusted
OR (95% CI)
Adjusteda
OR (95% CI)
Change in VO2peak (1 MET)b - 0.50 (0.29, 0.71) 0.46 (0.25, 0.67) - 0.72 (0.62, 0.83) 0.73 (0.63, 0.85)
Stable 24.8 (3.19) Ref. Ref. 161 (30.6) Ref. Ref.
Decreased 24.1 (3.71)  − 0.73 (− 1.23, − 0.23)  − 0.64 (− 1.15, − 0.14) 96 (38.1) 1.40 (1.02, 1.91) 1.35 (0.98, 1.87)
Increased 25.1 (2.89) 0.24 (− 0.67, 1.16) 0.24 (− 0.68, 1.15) 13 (22.8) 0.67 (0.35, 1.28) 0.70 (0.36, 1.34)

B unstandardized beta coefficient, CI confidence interval, MCI mild cognitive impairment, MET metabolic equivalent of task, MoCA Montreal Cognitive Assessment scale, OR odds ratio, Ref. reference, SD standard deviation, VO2peak peak oxygen uptake

aAdjusted for sex, cohabitation status, self-reported memory problems at baseline, and intervention group

bAdditionally adjusted for VO2peak at baseline