Creatine monohydrate reduced the level of exercise-induced muscle damage as an acute training response, although this trend was reversed as a chronic training response.

Creatine monohydrate may be an ergogenic supplement to accelerate recovery following a single bout of strenuous exercise.

The increased level of exercise-induced muscle damage after several weeks of training and creatine monohydrate supplementation may suggest a possibly greater tolerance of training stresses, given that long-term creatine monohydrate supplementation is known to enhance training adaptation.