Table 1.
Demographic and clinical characteristics of PD patients with and without depression
| DPD (N = 10) | NDPD (N = 19) | P | |
|---|---|---|---|
| Age (years) | 59.79 ± 10.45 | 63.40 ± 12.27 | 0.41 |
| Sex(female/male) | 6/4 | 8/11 | 0.36 |
| Course of PD (years) | 2.55 ± 2.98 | 2.15 ± 1.77 | 0.65 |
| MDS-UPDRS III | 21.75 ± 7.26 | 18.89 ± 7.07 | 0.32 |
| MMSE | 26.90 ± 2.33 | 27.84 ± 1.57 | 0.21 |
| HAMD | 12 (11, 26) | 3.5 (2, 5) | < 0.0001* |
| Whole-brain complexity | 1.2 ± 0.03 | 1.26 ± 0.03 | 0.0005* |
DPD, Parkinson’s disease with depression; NDPD, Parkinson’s disease without depression; MDS-UPDRS III, part III of MDS-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS); MMSE, Mini–Mental State Exam; HAMD, Hamilton Depression Scale.*p < 0.05