Table 5.

Inter-reader concordance on individual indicators used for the construction of the score

		Cohen’s kappa
Individual features	Capsular abutment	0.34 (0.07–0.61)
	Tumor-capsule interface > 10 mm	0.44 (0.24–0.64)
	Irregular or spiculated margin	0.59 (0.37–0.82)
	Bulging prostatic contour	0.59 (0.41–0.77)
	Asymmetry of neurovascular bundle	0.34 (0.005–0.67)
	Measurable extraprostatic disease	0.84 (0.63–1)
Scoring approaches	mEPE-score
	Score Positive diagnosis (> 3)	0.61 (0.46–0.75) 0.65 (0.46–0.84)
	ESUR-score
	Score Positive diagnosis (> 3)	0.70 (0.58–0.81) 0.66 (0.49–0.84)
	mEPE-grade
	Score Positive diagnosis (> 1)	0.73 (0.60–0.86) 0.68 (0.50–0.86)
	Early-and-late-EPE
	Score Positive diagnosis (> 1)	0.56 (0.36–0.75) 0.59 (0.38–0.81)