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. 2022 Feb 14;52(7):1667–1688. doi: 10.1007/s40279-022-01644-9

Table 2.

Meta-analysis summary

Outcome Summary of findings Quality of evidence synthesis (GRADE)
K(k) N(n) SMD (95% CI) p-value I2 (%) Imprecision Inconsistency Risk of bias Overall quality
CK 1 h (ecc) 2 (2) 58 (58) 0.85 (− 0.93 to 2.63) 0.349 87.5 − 1 − 1 None Low
CK 1 h (hit) Data could not be pooled (K(k) = 1(1))
CK 24 h (ecc) 11 (16) 373 (470) 0.12 (− 0.31 to 0.54) 0.595 63.1 None − 1 None Moderate
CK 24 h (hit) 5 (6) 105 (113) − 0.85 (− 1.61 to − 0.08) 0.030 58.6 None − 1 None Moderate
CK 48 h (ecc) 11 (16) 373 (470) − 0.04 (− 0.37 to 0.30) 0.834 50.6 None − 1 None Moderate
CK 48 h (hit) 4 (5) 81 (89) − 1.36 (− 2.51 to − 0.20) 0.022 77.3 − 1 − 1 None Low
CK 72 h (ecc) 10 (15) 353 (450) − 0.15 (− 0.57 to 0.27) 0.494 61.5 None − 1 None Moderate
CK 72 h (hit) Data could not be pooled (K(k) = 1(2))
CK 96 h (ecc) 6 (10) 243 (326) − 0.04 (− 0.43 to 0.35) 0.839 39.4 None None None High
CK 96 h (hit) Data could not be pooled (K(k) = 1(1))
CK 168 h (ecc) 2 (3) 71 (85) − 0.62 (− 1.05 to − 0.18) 0.006 0 − 1 None None Moderate
CK 168 h (hit) No studies
DOMS 1 h (ecc) 4 (4) 64 (90) 0.00 (− 1.09 to 1.10) 0.998 69.4 − 1 − 1 None Moderate
DOMS 1 h (hit) 9 (10) 149 (229) − 1.10 (− 1.81 to − 0.40) 0.002 78.1 None − 1 None Moderate
DOMS 24 h (ecc) 13 (17) 401 (497) − 0.51 (− 1.10 to 0.09) 0.094 75.9 None − 1 None Moderate
DOMS 24 h (hit) 20 (25) 297 (497) − 0.89 (− 1.48 to − 0.29) 0.003 77.4 None − 1 None Moderate
DOMS 48 h (ecc) 12 (16) 375 (471) − 0.48 (− 0.79 to − 0.16) 0.003 49.1 None None None High
DOMS 48 h (hit) 11 (16) 164 (330) − 0.82 (− 1.57 to − 0.07) 0.031 83.2 None − 1 None Moderate
DOMS 72 h (ecc) 10 (14) 340 (423) − 0.55 (− 0.86 to − 0.23) 0.001 33.4 None None None High
DOMS 72 h (hit) 4 (6) 69 (104) 0.09 (− 0.40 to 0.59) 0.718 23.9 − 1 None None Moderate
DOMS 96 h (ecc) 8 (12) 296 (379) − 0.41 (− 0.62 to − 0.21) < 0.001 0 None None None High
DOMS 96 h (hit) Data could not be pooled (K(k) = 1(1))
DOMS 168 h (ecc) 2 (2) 42 (55) − 0.78 (− 1.87 to 0.31) 0.160 75.0 − 1 − 1 None Low
DOMS 168 h (hit) Data could not be pooled (K(k) = 1(1))
Power 1 h (ecc) 2 (2) 33 (46) − 0.25 (− 0.58 to 0.07) 0.123 9.9 − 1 None None Moderate
Power 1 h (hit) 4 (5) 84 (174) − 0.22 (− 0.52 to 0.09) 0.160 14.3 − 1 None None Moderate
Power 24 h (ecc) 6 (8) 174 (201) 0.34 (0.06 to 0.62) 0.018 0 None None None High
Power 24 h (hit) 17 (29) 278 (676) 0.22 (0.004 to 0.43) 0.046 74.6 None − 1 None Moderate
Power 48 h (ecc) 7 (10) 196 (245) 0.47 (0.22 to 0.73) < 0.001 0 None None None High
Power 48 h (hit) 10 (14) 163 (357) − 0.02 (− 0.12 to 0.07) 0.608 4.8 None None None High
Power 72 h (ecc) 4 (5) 115 (129) 0.62 (0.27 to 0.98) 0.001 0 None None None High
Power 72 h (hit) 2 (3) 25 (52) − 0.01 (− 0.51 to 0.49) 0.969 0 − 1 None None Moderate
Power 96 h (ecc) 2 (3) 71 (85) 0.41 (− 0.02 to 0.84) 0.062 0 − 1 None None Moderate
Power 96 h (hit) 2 (2) 37 (37) 0.05 (− 0.59 to 0.70) 0.873 0 − 1 None None Moderate
Power 168 h (ecc) 2 (3) 71 (85) 0.36 (− 0.23 to 0.95) 0.228 0 − 1 None None Moderate
Power 168 h (hit) Data could not be pooled (K(k) = 1(1))
Strength 1 h (ecc) 2 (2) 38 (38) 2.31 (− 4.25 to 8.88) 0.490 97.2 − 1 − 1 None Low
Strength 1 h (hit) 2 (2) 42 (42) − 0.11 (− 0.72 to 0.50) 0.720 0 − 1 None None Moderate
Strength 24 h (ecc) 8 (10) 224 (258) 0.74 (− 0.78 to 2.26) 0.340 76.0 None − 1 None Moderate
Strength 24 h (hit) 3 (3) 62 (62) 0.12 (− 0.38 to 0.62) 0.637 0 − 1 None None Moderate
Strength 48 h (ecc) 8 (10) 224 (258) 0.84 (− 0.89 to 2.57) 0.339 78.9 None − 1 None Moderate
Strength 48 h (hit) Data could not be pooled (K(k) = 1(1))
Strength 72 h (ecc) 8 (10) 224 (258) 0.64 (− 0.51 to 1.79) 0.276 74.9 None − 1 None Moderate
Strength 72 h (hit) Data could not be pooled (K(k) = 1(1))
Strength 96 h (ecc) 5 (7) 165 (199) − 0.30 (− 0.78 to 0.17) 0.212 36.8 None None None High
Strength 96 h (hit) No studies
Strength 168 h (ecc) 2 (3) 71 (85) − 0.09 (− 0.51 to 0.34) 0.691 0 − 1 None None Moderate
Strength 168 h (hit) No studies
Perceived recovery 24 h (ecc) 2 (6) 159 (242) 0.15 (− 0.29 to 0.59) 0.493 0 None None None High
Perceived recovery 24 h (hit) 5 (5) 79 (135) 0.66 (0.29 to 1.03) 0.001 34.3 − 1 None None Moderate
Perceived recovery 48 h (ecc) 2 (6) 159 (242) 0.14 (− 0.11 to 0.39) 0.274 0 None None None High
Perceived recovery 48 h (hit) 2 (2) 38 (76) − 0.02 (− 0.38 to 0.34) 0.901 0 − 1 None None High
Perceived recovery 72 h (ecc) 2 (6) 159 (242) 0.55 (0.29 to 0.80)  < 0.001 0 None None None High
Perceived recovery 72 h (hit) No studies
Perceived recovery 96 h (ecc) 2 (6) 159 (242) 0.38 (0.12 to 0.64) 0.004 2.9 None None None High
Perceived recovery 96 h (hit) No studies
Endurance 24 h (ecc) No studies
Endurance 24 h (hit) 5 (5) 51 (102) − 0.14 (− 0.40 to 0.13) 0.316 73.6 − 1 − 1 − 1 Very low
Endurance 48 h (ecc) No studies
Endurance 48 h (hit) 2 (2) 24 (46) 0.12 (− 0.16 to 0.40) 0.400 0 − 1 None None Moderate
Flexibility 1 h (ecc) No studies
Flexibility 1 h (hit) 3 (3) 62 (92) 2.14 (− 1.77 to 6.06) 0.283 92.9 − 1 − 1 None Low
Flexibility 24 h (ecc) Data could not be pooled (K(k) = 1(1))
Flexibility 24 h (hit) 3 (3) 55 (94) 1.52 (− 1.78 to 4.82) 0.367 92.6 − 1 − 1 None Low
Flexibility 48 h (ecc) 2 (2) 38 (38) 0.23 (− 0.41 to 0.87) 0.481 0 − 1 None None Moderate
Flexibility 48 h (hit) 3 (3) 62 (92) 2.23 (− 1.86 to 6.32) 0.286 93.3 − 1 − 1 None Low
Flexibility 72 h (ecc) Data could not be pooled (K(k) = 1(1))
Flexibility 72 h (hit) Data could not be pooled (K(k) = 1(1))
Flexibility 96 h (ecc) Data could not be pooled (K(k) = 1(1))
Flexibility 96 h (hit) Data could not be pooled (K(k) = 1(1))

CK creatine kinase, DOMS delayed onset muscle soreness, ecc eccentric exercise, GRADE Grading of Recommendations Assessment, Development and Evaluation, h hour, hit high-intensity exercise, K(k) unique studies (observation points), N(n) unique participants (observation points), SMD standardised mean difference, 95% CI 95% confidence interval