Table 1.

Molecular measures of the 426 and of the subset of 384 female PM carrier groups.

Molecular measures	Total Group, n = 426			Subset, n = 384			Unstable, n = 361	Stable, n = 23	Welch Two Sample t-test	Actual value
	n	Mean	Std. Dev	n	Mean	Std. Dev	Mean ± Std. Err	Mean ± Std. Err
CGG repeat	425**	92.08	22.94	383**	90.40	19.00	91.69 ± 0.98	70.13 ± 2.65	< 0.0001	~ 3e−8
AGG	426	0.75	0.78	384	0.78	0.79	0.72 ± 0.04	1.65 ± 0.12	< 0.0001	~ 6e−8
AR	424	0.54	0.17	382	0.53	0.16	0.53 ± 0.008	0.58 ± 0.04	0.135153
FMR1 mRNA	401	2.18	0.91	361	2.21	0.89	2.24 ± 0.05	1.60 ± 0.18	0.001696
Age	423	42.49	17.18	381	42.01	16.84	42.80 ± 0.87	29.76 ± 3.99	0.003882
AUC1	413	0.71	0.23	384	0.71	0.21	0.69 ± 0.01	0.99 ± 0.007	< 0.0001	~ 8e−60
AUC2	413	0.29	0.23	384	0.29	0.21	0.31 ± 0.01	0.01 ± 0.007	< 0.0001	~ 9e−60
D1	412	1.41	0.61	384	1.36	0.32	1.40 ± 0.02	0.77 ± 0.007	< 0.0001	~ 4e−120
D2	411	2.44	2.09	383	2.50	2.01	2.66 ± 0.10	0 ± 0	< 0.0001	~ 2e−83
AGG
0		197 (46.2%)*			171 (44.5%)*		170 (47.1%)*	1 (4.3%)*
1		138 (32.4%)*			127 (33.1%)*		121 (33.5%)*	6 (26.1%)*
2		91 (21.4%)*			86 (22.4%)*		70 (19.4%)*	16 (69.6%)*

*Percentage of females relative to the total number, presenting with 0, 1 or 2 AGG interruptions.

**Number of females for whom the CGG repeat allele size was included (one participants was removed as she was a double heterozygous- two premutation alleles).