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. 2022 Jun 21;12:10435. doi: 10.1038/s41598-022-14287-7

Table 2.

Results of repeated variables over the follow-up study period eyes with mCNV (n = 41).

Variable baseline 1 Month 6 Months 12 Months p value
BCVA (logMAR) 0.48 ± 0.34 0.34 ± 0.29 0.26 ± 0.24a 0.28 ± 0.25b 0.003A
Ellipsoid zone disruption (n) 37 (90.5%) 20 (61.9%) c 3 (4.8%)d 6 (9.5%)d  < 0.001Q
Subretinal hyperreflective exudation (n) 39 (95.1%) 19 (46.1%) d 3 (7.3%)d 1 (2.4%)d  < 0.001Q
Intraretinal cysts (n) 11 (26.8%) 10 (24.4%) 4 (9.8%)e 2 (4.9%)f 0.002Q
Subretinal fluid (n) 17 (41.5%) 3 (7.3%) g 1 (2.4%)d 2 (4.9%)d  < 0.001Q
CNV area (mm2) 0.61 ± 0.58 0.54 ± 0.55 0.50 ± 0.47 0.49 ± 0.48 0.736A
Subretinal fibrosis (n) 0 (0%) 0 (0%) 10 (24.4%)h 19 (46.3%)d < 0.001Q

Significant values are in bold.

AANOVA test; QCochran’s Q test; a0.004 (Tukey HSD vs baseline); b0.009 (Tukey HSD vs baseline); c0.001(McNemar vs baseline); d< 0.001(McNemar vs baseline); e0.039 (McNemar vs baseline); f0.012 (McNemar vs baseline); g0.001 (McNemar vs baseline); h0.002 (McNemar vs baseline).

BCVA Best-Corrected Visual Acuity, CNV Choroidal neovascularization, logMAR logarithm of the minimal angle of resolution, mm millimeter.