Table 1.

Physiological ranges of model parameters.

Parameter	Description	Physiological range	Median	References
Ka	Protein–protein association constant	0.001 ~ 1 (nM−1)	0.05	41,60,61
λ	Protein degradation rate constant	0.017 ~ 0.693 (h−1)	0.027	62
C	Protein synthesis rate	1 ~ 1000 (nM/h)	~ 100	42
λm	mRNA degradation rate constant	0.017 ~ 2.687 (h−1)	0.085	63
K	Dissociation constant of repressor-promoter	0.001 ~ 1 (nM−1)		64
n	Cooperativity of promoter activity	1 ~ 2		65