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. 2022 Jun 21;6:41. doi: 10.1038/s41698-022-00289-1

Fig. 5. Targeted proteomics of CTC subtypes.

Fig. 5

a Heatmap of proteomic expression in CTC subtypes, including AR-N terminal (AR_N), AR-C terminal (AR_C), PSMA, EpCAM, E-Cadherin, N-Cadherin, Vimentin (VIM), PCNA, and β-catenin. b Immunofluorescence and image mass cytometry images of representative CTC subtypes. c Comparisons of proteomic expressions among CTC subtypes. Center line of box: median; upper/lower hinges of box: 75% or 25% quartile; upper/lower whiskers of box: hinge ± 1.5*IQR (inter-quartile range). *p < 0.05, **p < 0.01, ***p < 0.001.