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. 2022 Jun 21;6:42. doi: 10.1038/s41698-022-00287-3

Fig. 3. The detection strategies of sEV PD-L1.

Fig. 3

a The detection methods of sEV PD-L1 were divided into three categories based on the qualitative detection and quantitative determination. b Schematic of ELISA to measure PD-L1 levels on the surface of sEVs. c PD-L1 level were quantified by anti-PD-L1 antibody-modified Au@Ag@MBA surface-enhanced Raman scattering (SERS) tags. d An efficient and sensitive quantitation method for circulating sEV PD-L1 using aptamer-induced thermophoretic quantitation. e Surface plasmon resonance (SPR) biosensor to detect the sEV PD-L1.