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. 2022 Jun 21;12:10399. doi: 10.1038/s41598-022-14511-4

Table 2.

Comparison of mean Gleason scores of EBV-positive and EBV-negative groups using independent samples t-test.

Histopathological parameter(s) EBV-positive & EBV-negative samples N Mean SD p-value
Gleason score major Negative 66 3.84 0.58 0.038*
Positive 33 4.12 0.64
Gleason score minor Negative 66 3.90 0.62 0.18
Positive 33 4.12 0.78
Gleason score total Negative 66 7.75 1.03 0.042*
Positive 33 8.24 1.22
Prognostic grade group Negative 63 3.68 1.35 0.71
Positive 36 3.58 1.25

The table shows the mean score comparison of Gleason major, Gleason minor, and total Gleason scores in between positive and negative samples. The histopathological analysis of tumor tissues was done as per the International Society of Urological Pathology (ISUP) 2014 and later ratified by WHO 2016 as the prostate cancer grade group system.

*p < 0.05 was considered significant using an independent sample t-test.