Table 2.
50 significant age-related acetylation changes in mouse hearts. Bold numbers indicate significance (FDR < 0.1). Ordered by P-value in Young vs Old Control Comparison. Full results can be found in Appendix 2
| Peptide | Maps to Proteins | Fold Change Relative to Old Control | ||
|---|---|---|---|---|
| Young | Old + ELAM | Old + NMN | ||
| ASFTK[+ 42]SLQGIR | sp|Q02788|CO6A2_MOUSE:tr|D3Z7D5|D3Z7D5_MOUSE | 0.06 | 0.98 | 0.58 |
| LVEK[+ 42]FLEEAK | sp|P07758|A1AT1_MOUSE:sp|P22599|A1AT2_MOUSE:sp|Q00896|A1AT3_MOUSE:sp|Q00897|A1AT4_MOUSE:sp|Q00898|A1AT5_MOUSE:tr|A0A0A0MQA3|A0A0A0MQA3_MOUSE:tr|A0A0R4J0X5|A0A0R4J0X5_MOUSE | 2.22 | 1.31 | 1.14 |
| DLSYK[+ 42]DR | sp|O70433|FHL2_MOUSE | 0.16 | 1.19 | 1.19 |
| MEIQEIQLK[+ 42]EAK | sp|P58771|TPM1_MOUSE:tr|B7ZNL3|B7ZNL3_MOUSE:tr|E9Q448|E9Q448_MOUSE:tr|E9Q450|E9Q450_MOUSE:tr|E9Q452|E9Q452_MOUSE:tr|E9Q453|E9Q453_MOUSE:tr|E9Q454|E9Q454_MOUSE:tr|E9Q455|E9Q455_MOUSE:tr|E9Q456|E9Q456_MOUSE:tr|F8WID5|F8WID5_MOUSE:tr|G5E8R0|G5E8R0_MOUSE:tr|G5E8R1|G5E8R1_MOUSE:tr|G5E8R2|G5E8R2_MOUSE:sp|P58771-2|TPM1_MOUSE:tr|Q8BP43|Q8BP43_MOUSE:tr|Q8BSH3|Q8BSH3_MOUSE | 2.60 | 1.15 | 1.81 |
| VFDK[+ 42]EGNGTVMGAEIR | sp|Q60605|MYL6_MOUSE:sp|Q60605-2|MYL6_MOUSE | 22.73 | 1.84 | 1.46 |
| HQIQSYTC[+ 57]EIDALK[+ 42]GTNDSLMR | sp|P31001|DESM_MOUSE | 3.29 | 1.44 | 1.76 |
| HQGVMVGMGQK[+ 42]DSYVGDEAQSK | sp|P60710|ACTB_MOUSE:sp|P62737|ACTA_MOUSE:sp|P63260|ACTG_MOUSE:sp|P63268|ACTH_MOUSE:sp|P68033|ACTC_MOUSE:sp|P68134|ACTS_MOUSE:tr|D3YZY0|D3YZY0_MOUSE:tr|D3Z2K3|D3Z2K3_MOUSE:tr|E9Q5F4|E9Q5F4_MOUSE:tr|E9Q606|E9Q606_MOUSE:tr|G3UYG0|G3UYG0_MOUSE:tr|G3UZ07|G3UZ07_MOUSE | 4.62 | 1.64 | 2.46 |
| LTMFGEK[+ 42]LK | sp|P51667|MLRV_MOUSE:sp|Q62082|MYL10_MOUSE:tr|A0A0G2JDZ4|A0A0G2JDZ4_MOUSE:tr|A0A0G2JE15|A0A0G2JE15_MOUSE:tr|D3YUI7|D3YUI7_MOUSE:tr|D3YW14|D3YW14_MOUSE:tr|D3Z0I3|D3Z0I3_MOUSE:tr|E9Q8Y0|E9Q8Y0_MOUSE:tr|E9QNY3|E9QNY3_MOUSE:sp|Q62082-2|MYL10_MOUSE:sp|Q62082-3|MYL10_MOUSE:sp|P97457|MLRS_MOUSE:tr|A0A0U1RP93|A0A0U1RP93_MOUSE:tr|A0A0U1RQ36|A0A0U1RQ36_MOUSE | 18.04 | 1.60 | 0.79 |
| VVK[+ 42]QASEGPLK | sp|P16858|G3P_MOUSE:tr|S4R1W1|S4R1W1_MOUSE:tr|A0A0A0MQF6|A0A0A0MQF6_MOUSE:tr|S4R257|S4R257_MOUSE | 3.43 | 1.45 | 2.14 |
| VYINLDK[+ 42]ETK | sp|P52503|NDUS6_MOUSE | 3.43 | 1.45 | 2.14 |
| VYINLDKETK[+ 42] | sp|P52503|NDUS6_MOUSE | 4.47 | 1.68 | 2.33 |
| EITALAPSTMKIK[+ 42] | sp|P60710|ACTB_MOUSE:sp|P62737|ACTA_MOUSE:sp|P63260|ACTG_MOUSE:sp|P63268|ACTH_MOUSE:sp|P68033|ACTC_MOUSE:sp|P68134|ACTS_MOUSE:tr|B1ATY1|B1ATY1_MOUSE:tr|E9Q1F2|E9Q1F2_MOUSE:tr|F8WGM8|F8WGM8_MOUSE | 0.24 | 1.19 | 0.60 |
| TVTNNLK[+ 42]SLEAQAEK | sp|P58771|TPM1_MOUSE:tr|B7ZNL3|B7ZNL3_MOUSE:tr|E9Q452|E9Q452_MOUSE:tr|E9Q454|E9Q454_MOUSE:tr|E9Q455|E9Q455_MOUSE:tr|F8WID5|F8WID5_MOUSE:tr|G5E8R0|G5E8R0_MOUSE:tr|G5E8R1|G5E8R1_MOUSE:sp|P58771-2|TPM1_MOUSE:tr|Q8BSH3|Q8BSH3_MOUSE | 27.23 | 1.21 | 1.90 |
| VYFAEK[+ 42]VTSLGK | sp|Q9DCT8|CRIP2_MOUSE:tr|A0A0G2JF37|A0A0G2JF37_MOUSE | 7.14 | 1.47 | 2.78 |
| AFFK[+ 42]GAWSNVLR | sp|P48962|ADT1_MOUSE:sp|P51881|ADT2_MOUSE | 28.60 | 1.39 | 2.93 |
| SFHK[+ 42]TC[+ 57]FHC[+ 57] | sp|P50462|CSRP3_MOUSE | 12.39 | 3.39 | 4.87 |
| VASNLNLKPGEC[+ 57]LK[+ 42]VR | sp|P16045|LEG1_MOUSE | 3.41 | 1.37 | 1.95 |
| GTQC[+ 57]EK[+ 42]IVQK | sp|Q9R0Y5|KAD1_MOUSE:tr|A0A0A6YXW8|A0A0A6YXW8_MOUSE:sp|Q9R0Y5-2|KAD1_MOUSE:tr|Z4YN97|Z4YN97_MOUSE | 2.25 | 1.25 | 1.60 |
| AITATQK[+ 42]TVDGPSGK | tr|D3YYI5|D3YYI5_MOUSE:sp|P16858|G3P_MOUSE:tr|S4R1W1|S4R1W1_MOUSE:tr|V9GX06|V9GX06_MOUSE:tr|V9GXA7|V9GXA7_MOUSE:tr|A0A0A0MQF6|A0A0A0MQF6_MOUSE:tr|S4R257|S4R257_MOUSE | 4.38 | 2.02 | 2.47 |
| NVLINK[+ 42]DIR | sp|P14211|CALR_MOUSE | 13.00 | 1.08 | 0.89 |
| VESQLK[+ 42]ILIRPLYSNPPLNGAR | sp|P05202|AATM_MOUSE | 2.27 | 1.46 | 1.26 |
| QWHNDC[+ 57]FNC[+ 57]KK[+ 42] | sp|O70433|FHL2_MOUSE | 3.34 | 1.23 | 1.88 |
| C[+ 57]GSSLVDK[+ 42]PFAAK | sp|O70433|FHL2_MOUSE | 0.06 | 0.81 | 0.86 |
| QWHNDC[+ 57]FNC[+ 57]K[+ 42]K | sp|O70433|FHL2_MOUSE | 9.50 | 1.70 | 0.89 |
| EC[+ 57]FVC[+ 57]TAC[+ 57]K[+ 42]K | sp|O70433|FHL2_MOUSE | 2.84 | 0.74 | 0.96 |
| EC[+ 57]FVC[+ 57]TAC[+ 57]KK[+ 42] | sp|O70433|FHL2_MOUSE | 4.27 | 1.19 | 1.11 |
| VINDFVEKGTQGK[+ 42] | sp|P07758|A1AT1_MOUSE:sp|P22599|A1AT2_MOUSE:sp|Q00896|A1AT3_MOUSE:sp|Q00897|A1AT4_MOUSE:sp|Q00898|A1AT5_MOUSE:tr|A0A0A0MQA3|A0A0A0MQA3_MOUSE:tr|A0A0R4J0X5|A0A0R4J0X5_MOUSE | 2.65 | 1.25 | 1.26 |
| C[+ 57]VSK[+ 42]YLDIHER | sp|P62073|TIM10_MOUSE | 2.65 | 1.25 | 1.26 |
| VINDFVEK[+ 42]GTQGK | sp|P07758|A1AT1_MOUSE:sp|P22599|A1AT2_MOUSE:sp|Q00896|A1AT3_MOUSE:sp|Q00897|A1AT4_MOUSE:sp|Q00898|A1AT5_MOUSE:tr|A0A0A0MQA3|A0A0A0MQA3_MOUSE:tr|A0A0R4J0X5|A0A0R4J0X5_MOUSE | 3.90 | 1.04 | 1.27 |
| K[+ 42]FLMEC[+ 57]R | sp|Q60876|4EBP1_MOUSE | 3.36 | 1.18 | 1.34 |
| MQMLK[+ 42]LDKENAIDR | sp|P58774|TPM2_MOUSE:tr|A2AIM4|A2AIM4_MOUSE:tr|A2AIM5|A2AIM5_MOUSE:sp|P58774-2|TPM2_MOUSE | 2.38 | 1.44 | 1.35 |
| MQMLK[+ 42]LDK | sp|P21107|TPM3_MOUSE:sp|P58771|TPM1_MOUSE:sp|P58774|TPM2_MOUSE:tr|A0A0R4J1P2|A0A0R4J1P2_MOUSE:tr|A2AIM4|A2AIM4_MOUSE:tr|A2AIM5|A2AIM5_MOUSE:tr|B7ZNL3|B7ZNL3_MOUSE:tr|E9Q448|E9Q448_MOUSE:tr|E9Q450|E9Q450_MOUSE:tr|E9Q452|E9Q452_MOUSE:tr|E9Q454|E9Q454_MOUSE:tr|E9Q5J9|E9Q5J9_MOUSE:tr|F8WID5|F8WID5_MOUSE:sp|P58771-2|TPM1_MOUSE:sp|P58774-2|TPM2_MOUSE:tr|Q8BP43|Q8BP43_MOUSE:tr|Q8BSH3|Q8BSH3_MOUSE:tr|S4R2U0|S4R2U0_MOUSE | 2.33 | 1.22 | 1.38 |
| ENLNK[+ 42]LMTNLK | sp|Q02566|MYH6_MOUSE:sp|Q5SX39|MYH4_MOUSE | 0.04 | 1.29 | 1.39 |
| C[+ 57]AADLGLK[+ 42]R | sp|P70349|HINT1_MOUSE | 2.02 | 1.16 | 1.41 |
| FGESEK[+ 42]C[+ 57]PR | sp|P50462|CSRP3_MOUSE | 2.38 | 1.24 | 1.42 |
| ENQNFC[+ 57]VPC[+ 57]YEK[+ 42]QYALQC[+ 57]VQC[+ 57]K | sp|O70433|FHL2_MOUSE | 2.03 | 1.33 | 1.55 |
| LAAEK[+ 42]GIDLTQVK | sp|Q8BMF4|ODP2_MOUSE | 3.36 | 1.12 | 1.78 |
| LSC[+ 57]LYGK[+ 42]IYQR | sp|Q71RI9|KAT3_MOUSE:tr|A0A0G2JGE1|A0A0G2JGE1_MOUSE:sp|Q71RI9-2|KAT3_MOUSE | 2.59 | 1.36 | 1.79 |
| VFVSPLAK[+ 42]K | sp|Q8BMF4|ODP2_MOUSE | 13.89 | 3.18 | 1.98 |
| ALDSTTVAAHESEIYC[+ 57]K[+ 42]VC[+ 57]YGR | sp|P50462|CSRP3_MOUSE | 3.68 | 2.07 | 2.72 |
| LKPGEC[+ 57]LK[+ 42]VR | sp|P16045|LEG1_MOUSE | 7.96 | 2.02 | 2.91 |
| VFVSPLAKK[+ 42] | sp|Q8BMF4|ODP2_MOUSE | 6.69 | 3.27 | 2.06 |
| DFGSFEK[+ 42]FKEK | sp|P09671|SODM_MOUSE | 2.04 | 1.22 | 1.55 |
| NYK[+ 42]TAPFDSR | sp|P56391|CX6B1_MOUSE | 2.23 | 1.25 | 1.88 |
| HPK[+ 42]FEEILTR | sp|P07310|KCRM_MOUSE:sp|KCRM_HUMAN| | 6.57 | 2.75 | 4.08 |
| MM[+ 16]DFETFLPMLQHISKNK[+ 42] | sp|P09542|MYL3_MOUSE:tr|A0A0G2JDM3|A0A0G2JDM3_MOUSE:tr|A0A0G2JDW2|A0A0G2JDW2_MOUSE | 8.14 | 1.19 | 3.35 |
| GVWK[+ 42]GLFAR | sp|Q8VEM8|MPCP_MOUSE:tr|G5E902|G5E902_MOUSE | 0.27 | 1.10 | 0.71 |
| TGEGFYKYK[+ 42] | sp|Q61425|HCDH_MOUSE | 3.27 | 1.25 | 1.88 |
| HGC[+ 57]TVLTALGTILK[+ 42]K | sp|P04247|MYG_MOUSE | 3.12 | 1.17 | 1.65 |
| VAQLC[+ 57]DFNPK[+ 42]SSK | sp|Q6IRU5|CLCB_MOUSE:sp|Q6IRU5-2|CLCB_MOUSE | 4.06 | 0.93 | 1.94 |