Table 3.
Significant Protein Abundance Association with Ea/Aa. Bold numbers indicate significance (FDR < 0.1). Ordered by lowest adjusted P-value across all comparisons. Full results can be found in Appendix 1
| Protein | Slope of Association with Ea/Aa | |||
|---|---|---|---|---|
| Young | Old Control | Old ELAM | Old NMN | |
| HPRT | -3.57 | -0.70 | 0.31 | -0.01 |
| EGFR | 0.24 | 0.24 | -1.49 | -0.12 |
| FA10 | -1.37 | -1.12 | -1.18 | -0.36 |
| A2AP | 0.71 | -0.43 | -0.76 | 0.04 |
| HEP2 | 0.96 | -0.42 | -1.30 | 0.17 |
| TACC2 | -0.56 | -0.65 | 0.58 | -0.10 |
| RNF25 | 0.56 | -0.14 | -1.15 | -0.34 |
| PDK4 | 0.50 | 1.24 | 1.32 | 0.05 |
| PALLD | -1.41 | 0.27 | -1.96 | -0.53 |
| EST1C | 0.03 | -0.41 | -1.22 | -0.32 |
| A1AT4 | 0.73 | -0.49 | -0.91 | -0.34 |
| MT2 | -0.28 | 0.73 | 1.02 | 0.61 |
| A1AT1 | 0.53 | -0.18 | -0.75 | -0.25 |
| LIFR | -0.59 | 0.19 | -2.12 | -0.97 |
| HNRPK | -0.26 | -0.14 | 0.45 | 0.06 |
| AHNAK | -0.36 | -0.51 | 0.40 | -0.03 |
| TNNT2 | -0.71 | 0.05 | 0.62 | -0.18 |
| CPN2 | 0.11 | -0.72 | -0.87 | -0.15 |
| H2AX | -0.30 | 0.36 | 0.50 | 0.27 |
| FETUB | 0.19 | 0.03 | -0.51 | 0.39 |
| APOH | 0.37 | 0.33 | -0.73 | -0.06 |
| COF2 | -0.18 | 0.22 | 0.41 | -0.09 |
| ICA | 0.56 | 0.09 | -0.91 | -0.36 |
| EST1 | -0.08 | -0.16 | -0.76 | -0.24 |
| VTDB | -0.20 | 0.05 | -0.93 | 0.07 |
| SLIRP | 0.14 | -0.07 | -1.40 | -0.74 |
| A1AT2 | 0.30 | -0.08 | -0.65 | -0.15 |
| Hbb-bs | 0.51 | 0.39 | -0.58 | -0.27 |