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. 2022 Mar 14;44(3):1269–1293. doi: 10.1007/s11357-022-00533-3

Table 3.

Gene ontology results of the 1096 genes, which included exons with very different PSI estimates in young and old animals. FDR – false discovery rate

GO biological process complete Number of reference genes (N = 16,036) Number of target genes (N = 1096) Fold enrichment FDR
Observed Expected
Actin filament–based process 388 55 28.59 1.92 3.46E − 02
Cellular nitrogen compound metabolic process 2149 101 158.34 0.64 6.11E − 03
Organonitrogen compound biosynthetic process 888 34 65.43 0.52 3.67E − 02
Cellular macromolecule biosynthetic process 969 36 71.4 0.50 1.18E − 02

The reference gene list corresponds to all genes expressed in the analyzed brain tissue