Fig. 3.

Autophagy genes are required for CBD-mediated lifespan extension. A Lifespan of wild-type worms (N2) treated with 1 μM or vehicle treatment at 20℃. p values compared with control calculated using log-rank test. B, C Lifespan of worms fed with bacteria containing empty vector (EV) or vectors for RNAi of autophagy genes (vps-34, bec-1, and sqst-1), treated with CBD or untreated. *p ≤ 0.05, **p ≤ 0.01, *** p ≤ 0.001 by log-rank test. Data are representative of at least three independent experiments