Table 1.
Baseline characteristics of participants by levels of educational attainment
| Low | Intermediate | High | |
|---|---|---|---|
| N (%) | 72,659 (41.7) | 54,392 (31.2) | 47,110 (27.0) |
| Age, years (SD) | 64.4 (2.9) | 64.0 (2.8) | 63.8 (2.8) |
| Male (%) | 42.0 | 51.8 | 53.3 |
| Townsend deprivation index | − 1.3 (3.0) | − 2.0 (2.7) | − 2.0 (2.7) |
| Modifiable risk factors in middle or late life | |||
| Healthy diet score | 2.2 (1.1) | 2.3 (1.1) | 2.4 (1.1) |
| Moderate drinking (%) | 44.4 | 48.8 | 51.8 |
| Current smoking (%) | 9.7 | 7.7 | 5.7 |
| Regular physical activity (%) | 63.6 | 64.7 | 63.2 |
| Obesity (%) | 27.4 | 24.9 | 18.3 |
| Hypertension (%) | 72.7 | 69.8 | 64.2 |
| Diabetes (%) | 7.3 | 6.5 | 4.9 |
| Depression (%) | 18.9 | 16.6 | 16.2 |
| Social isolation (%) | 10.1 | 7.5 | 7.2 |
| Hearing problem (%) | 32.1 | 32.4 | 31.7 |
| Traumatic brain injury (%) | 0.1 | 0.1 | 0.1 |
| High cholesterol (%) | 31.7 | 28.9 | 24.3 |
| Cardiovascular diseases (%) | 11.3 | 9.6 | 6.8 |
| Number of the APOE ε4 alleles | |||
| Zero (%) | 73.5 | 73.7 | 73.8 |
| One (%) | 24.2 | 23.8 | 23.9 |
| Two (%) | 2.3 | 2.5 | 2.4 |
| PRS | |||
| Low (%) | 33.2 | 33.5 | 33.3 |
| Middle (%) | 33.3 | 33.3 | 33.5 |
| High (%) | 33.6 | 33.1 | 33.2 |
Data are mean (SD), or (%)