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. 2022 Apr 28;44(3):1551–1562. doi: 10.1007/s11357-022-00576-6

Table 3.

Correlations between the OCT-A paramers and levels of α-synuclein and NfL in tears

FAZ VDsM, fovea VDsM, parafovea VDdM, fovea VDdM, parafovea VDrID VDrPP
α-synuclein
ρ  − 0.10 0.04  − 0.21 0.10 0.08 0.08  − 0.21
P value 0.55 0.82 0.19 0.55 0.62 0.64 0.19
Adjusted ρ#  − 0.10 0.03  − 0.19 0.11 0.15 0.09  − 0.20
Adjusted P value# 0.57 0.84 0.26 0.51 0.37 0.61 0.22
NfL
ρ 0.14  − 0.13  − 0.19  − 0.16  − 0.13 0.09  − 0.33
P value 0.41 0.44 0.24 0.31 0.42 0.59 0.04*
Adjusted ρ# 0.15  − 0.14  − 0.05  − 0.14 0.01 0.12  − 0.31
Adjusted P value# 0.36 0.38 0.78 0.39 0.94 0.47 0.06

#Adjustment of age

OCT-A, optical coherence tomography angiography; FAZ, foveal avascular zone; VDsM, vessel density in the superficial plexus of the central macula; VDdM, vessel density in the deep plexus of the central macula; VDrID, vessel density in the radial peripapillary capillary layer of the disc region; VDrPP, vessel density in the radial peripapillary capillary layer of the peripapillary region. *P < 0.05