Table 3.

Univariate and multivariate analysis of risk factors for RFS.

Variables	Univariate analysis			Multivariate analysis
	No. of patients	1-year-RFS (%)	P value	HR(95%CI)	P value
Gender (n, %)			0.307
Male	15	73.0
Female	25	47.4
Age, years			0.014	——	0.148
<45	17	84.4
≥45	23	48.2
WBC count, *109/L			0.195
<100	36	58.5
≥100	4	NA
Hemoglobin, g/L			0.442
<100	34	58.7
≥100	6	83.3
Platelet count, *109/L			0.880
<100	32	64.5
≥100	8	60.0
Blast in bone marrow (%)			0.793
<50	13	65.3
≥50	27	59.0
Karyotype			0.974
Fav/int	37	61.5
Adv	3	66.7
Consolidation therapy			0.004	0.175(0.047-0.658)	0.010
HSCT	19	42.4
Chemotherapy	21	82.0
PTPN11*			1.000
Mut	4	66.7
WT	33	61.7
RUNX1*			0.451
Mut	3	NA
WT	34	61.0
IDH1*			0.320
Mut	3	NA
WT	34	59.8
Expression of TRIM32			0.025	——	0.128
Low	15	86.7
High	25	44.5

A total of 40 patients were included in the RFS analysis (6 patients were excluded for the lack of RFS data). A P value of less than 0.05 is indicated in italics and bold. * Next generation sequencing data is missing from 3 patients with RFS data. NA, not available.