Table 2.
Diagnostic performance of conventional CT image features for diagnosing metastatic lymph nodes.
AUC | Sensitivity | Specificity | PPV | NPV | |
---|---|---|---|---|---|
Total LNs | |||||
Size >10 mm | 0.638 (0.556, 0.713) | 0.588 (0.488, 0.706) | 0.687 (0.633, 0.700) | 0.755 (0.572, 0.799) | 0.606 (0.517, 0.690) |
Abnormal enhancement | 0.692 (0.619, 0.753) | 0.658 (0.537, 0.765) | 0.726 (0.646, 0.772) | 0.750 (0.653, 0.831) | 0.689 (0.574, 0.758) |
Calcification | 0.548 (0.466, 0.628) | 0.096 (0.039, 0.190) | 1.000 (0.955, 1.000) | 1.000 (0.590, 1.000) | 0.551 (0.467, 0.633) |
Cystic change | 0.555 (0.473, 0.635) | 0.110 (0.049, 0.205) | 1.000 (0.955, 1.000) | 1.000 (0.631, 1.000) | 0.555 (0.470, 0.637) |
Extra nodal extension | 0.507 (0.425, 0.588) | 0.014 (0.001, 0.074) | 1.000 (0.955, 1.000) | 1.000 (0.025, 1.000) | 0.529 (0.447, 0.611) |
Cervical root artifact affected LNs | |||||
Size >10 mm | 0.560 (0.416, 0.697) | 0.436 (0.390, 0.599) | 0.750 (0.703, 0.791) | 0.793 (0.613, 0.839) | 0.551 (0.402, 0.693) |
Abnormal enhancement | 0.647 (0.513, 0.772) | 0.613 (0.403, 0.802) | 0.701 (0.509, 0.811) | 0.712 (0.445, 0.883) | 0.637 (0.455, 0.799) |
Calcification | 0.520 (0.377, 0.661) | 0.040 (0.001, 0.204) | 1.000 (0.872, 1.000) | 1.000 (0.025, 1.000) | 0.529 (0.385, 0.671) |
Cystic change | NA | NA | NA | NA | NA |
Extra nodal extension | NA | NA | NA | NA | NA |
Data in parentheses indicate 95% confidence interval.
LNs, lymph nodes; PPV, positive predictive value; NPV, negative predictive value; NA, not applicable.