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. 2022 Jun 8;12:851244. doi: 10.3389/fonc.2022.851244

Table 2.

Diagnostic performance of conventional CT image features for diagnosing metastatic lymph nodes.

AUC Sensitivity Specificity PPV NPV
Total LNs
Size >10 mm 0.638 (0.556, 0.713) 0.588 (0.488, 0.706) 0.687 (0.633, 0.700) 0.755 (0.572, 0.799) 0.606 (0.517, 0.690)
Abnormal enhancement 0.692 (0.619, 0.753) 0.658 (0.537, 0.765) 0.726 (0.646, 0.772) 0.750 (0.653, 0.831) 0.689 (0.574, 0.758)
Calcification 0.548 (0.466, 0.628) 0.096 (0.039, 0.190) 1.000 (0.955, 1.000) 1.000 (0.590, 1.000) 0.551 (0.467, 0.633)
Cystic change 0.555 (0.473, 0.635) 0.110 (0.049, 0.205) 1.000 (0.955, 1.000) 1.000 (0.631, 1.000) 0.555 (0.470, 0.637)
Extra nodal extension 0.507 (0.425, 0.588) 0.014 (0.001, 0.074) 1.000 (0.955, 1.000) 1.000 (0.025, 1.000) 0.529 (0.447, 0.611)
Cervical root artifact affected LNs
Size >10 mm 0.560 (0.416, 0.697) 0.436 (0.390, 0.599) 0.750 (0.703, 0.791) 0.793 (0.613, 0.839) 0.551 (0.402, 0.693)
Abnormal enhancement 0.647 (0.513, 0.772) 0.613 (0.403, 0.802) 0.701 (0.509, 0.811) 0.712 (0.445, 0.883) 0.637 (0.455, 0.799)
Calcification 0.520 (0.377, 0.661) 0.040 (0.001, 0.204) 1.000 (0.872, 1.000) 1.000 (0.025, 1.000) 0.529 (0.385, 0.671)
Cystic change NA NA NA NA NA
Extra nodal extension NA NA NA NA NA

Data in parentheses indicate 95% confidence interval.

LNs, lymph nodes; PPV, positive predictive value; NPV, negative predictive value; NA, not applicable.