Table 3.
ECVS and ECVD for diagnosing metastatic lymph nodes.
| ECVS (%) | ECVD (%) | |||||||
|---|---|---|---|---|---|---|---|---|
| Total LNs(157) | Cervical root artifact affected LNs (59) | Total LNs (157) | Cervical root artifact affected LNs (59) | |||||
| Non-metastatic LNs (81) | Metastatic LNs (76) | Non-metastatic LNs (27) | Metastatic LNs (32) | Non-metastatic LNs (81) | Metastatic LNs (76) | Non-metastatic LNs (27) | Metastatic LNs (32) | |
| ECV (%) | 25.45 (18.15–31.17) | 39.18 (30.09–50.44) | 25.23 (14.20–33.93) | 35.96 (27.74–41.83) | 22.53 (16.97–29.09) | 42.41 (29.58–54.90) | 20.27 (9.53–31.48) | 41.19 (27.90–49.85) |
| p-value | <0.001 | <0.001 | <0.001 | <0.001 | ||||
| Cut-off Value (%) | 34.99 | 26.63 | 36.45 | 27.52 | ||||
| AUC | 0.793 (0.721, 0.853) | 0.716 (0.577, 0.830) | 0.813 (0.743, 0.871) | 0.756 (0.620, 0.862) | ||||
| Sensitivity | 0.671 (0.554, 0.775) | 0.815 (0.619, 0.937) | 0.645 (0.527, 0.751) | 0.778 (0.577, 0.914) | ||||
| Specificity | 0.901 (0.815, 0.956) | 0.593 (0.388, 0.776) | 0.914 (0.830, 0.965) | 0.704 (0.498, 0.862) | ||||
| PPV | 0.864 (0.750, 0.940) | 0.667 (0.482, 0.820) | 0.875 (0.759, 0.948) | 0.724 (0.528, 0.873) | ||||
| NPV | 0.745 (0.647, 0.828) | 0.762 (0.528, 0.918) | 0.733 (0.635, 0.816) | 0.760 (0.549, 0.906) | ||||
ECV is expressed as median with interquartile range in parentheses. Other data in parentheses indicate 95% confidence interval.
LNs, lymph nodes; ECV, extracellular volume; ECVS, SECT-derived ECV fraction; ECVD, DECT-derived ECV fraction; PPV, positive predictive value; NPV, negative predictive value.