Table 1.

Univariate cox regression analyses with respect to EFS, OS, LRC and FFDM.

Parameter	EFS				OS
	N	HR	95% CI	p-value	N	HR	95% CI	p-value
Sex male	1078	1.17	0.93 – 1.47	0.18	1094	1.17	0.91 – 1.51	0.22
Age > 60y	1078	1.51	1.26 – 1.81	<0.001	1078	1.57	1.28 – 1.93	<0.001
T-stage > 2	1074	1.93	1.58 – 2.36	<0.001	1090	2.17	1.72 – 2.75	<0.001
N-stage > 0	1074	1.3	1.03 – 1.64	0.025	1090	1.74	1.31 – 2.31	<0.001
UICC-stage > III	1047	1.48	1.2 – 1.82	<0.001	1063	1.92	1.49 – 2.46	<0.001
HPC+oral cavity	1078	2.48	2.02 – 3.05	<0.001	1094	2.98	2.39 – 3.72	<0.001
Chemotherapy NO	965	1.15	0.92 – 1.44	0.22	969	1.24	0.96 – 1.61	0.099
MTV	1078	1.02	1.02 – 1.02	<0.001	1094	1.02	1.02 – 1.02	<0.001
TLG	986	1.002	1.001 – 1.002	<0.001	1002	1.002	1.001 – 1.002	<0.001
SUVmax	986	1.02	1.01 – 1.03	<0.001	1002	1.02	1.01 – 1.04	<0.001
SUVmean	986	1.03	1.01 – 1.05	0.0075	1002	1.03	1.01 – 1.06	0.005
Parameter	LRC				FFDM
	N	HR	95% CI	p-value	N	HR	95% CI	p-value
Sex male	1094	1.005	0.728 – 1.388	0.97	1061	1.35	0.87 – 2.09	0.18
Age > 60y	1073	1.24	0.95 – 1.62	0.11	1060	1.4	1.01 – 1.96	0.047
T-stage > 2	1087	1.98	1.46 – 2.68	<0.001	1057	1.82	1.26 – 2.63	0.002
N-stage > 0	1087	1.02	0.74 – 1.42	0.89	1057	3.41	1.84 – 6.3	<0.001
UICC-stage > III	1060	1.36	1.01 – 1.83	0.046	1030	2.24	1.47 – 3.41	<0.001
HPC+oral cavity	1094	2.34	1.73 – 3.18	<0.001	1061	2.19	1.48 – 3.24	<0.001
Chemotherapy NO	960	0.994	0.713 – 1.386	0.97	961	2.01	1.25 – 3.23	0.004
MTV	1094	1.02	1.02 – 1.03	<0.001	1061	1.02	1.01 – 1.02	<0.001
TLG	992	1.002	1.001 – 1.002	<0.001	969	1.001	1.001 – 1.002	<0.001
SUVmax	992	1.03	1.01 – 1.04	0.011	969	1.03	1.01 – 1.05	0.015
SUVmean	992	1.03	1 – 1.06	0.027	969	1.04	1 – 1.07	0.05

PET parameters were included as metric parameters. Column ‘N’ shows the number of included patients in the respective analysis.