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TGF-β pathway gene expression in the TCGA cervical cancer dataset. (A) Optimal amount of clusters was calculated based on the silhouette value and was found to be two. (B) Multidimensional scaling shows a separate clustering of AC (yellow) and SCC (dark blue). (C) Heatmap showing unsupervised hierarchical clustering analysis of 144 SCC (dark grey) and 31 AC (light grey) patient samples on the X-axis and 153-gene TGF-β response signature genes on the Y-axis.
